Multicenter Study to Evaluate the Analgesic Efficacy of XP21L in Subjects With Pain Following Bunionectomy Surgery

NCT ID: NCT00375934

Last Updated: 2010-09-21

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

200 participants

Study Classification

INTERVENTIONAL

Study Start Date

2006-09-30

Brief Summary

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A multicenter study to evaluate the analgesic efficacy of XP21L in subjects with pain following bunionectomy surgery.

Detailed Description

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Conditions

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Pain, Postoperative

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Study Groups

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1

Group Type EXPERIMENTAL

diclofenac potassium (XP21L)

Intervention Type DRUG

25 mg capsule, every 6 hours

2

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type DRUG

Oral placebo capsule, every 6 hours

Interventions

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diclofenac potassium (XP21L)

25 mg capsule, every 6 hours

Intervention Type DRUG

Placebo

Oral placebo capsule, every 6 hours

Intervention Type DRUG

Other Intervention Names

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Zipsor Liquid Filled Capsule XP21L

Eligibility Criteria

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Inclusion Criteria

* 18-65 years of age
* Have undergone bunionectomy surgery
* Have achieved adequate post-surgical pain

Exclusion Criteria

* Confounding medical conditions which preclude study participation
* Participated in a study of another investigational drug or device within 30 days prior to randomization
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Xanodyne Pharmaceuticals

INDUSTRY

Sponsor Role lead

Responsible Party

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Xanodyne Pharmaceuticals, Inc.

Locations

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Investigative Site

Austin, Texas, United States

Site Status

Investigative Site

Houston, Texas, United States

Site Status

Investigative Site

San Marcos, Texas, United States

Site Status

Investigative Site

Salt Lake City, Utah, United States

Site Status

Countries

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United States

References

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Daniels SE, Riff D, Diamond E, Clark F, Boesing SE. An assessment of the efficacy and safety of diclofenac potassium liquid-filled capsules in patients with various levels of baseline pain intensity. Curr Med Res Opin. 2012 Jun;28(6):953-61. doi: 10.1185/03007995.2012.694363. Epub 2012 Jun 11.

Reference Type DERIVED
PMID: 22587481 (View on PubMed)

Daniels SE, Baum DR, Clark F, Golf MH, McDonnell ME, Boesing SE. Diclofenac potassium liquid-filled soft gelatin capsules for the treatment of postbunionectomy pain. Curr Med Res Opin. 2010 Oct;26(10):2375-84. doi: 10.1185/03007995.2010.515478.

Reference Type DERIVED
PMID: 20804444 (View on PubMed)

Related Links

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Other Identifiers

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XP21L-302

Identifier Type: -

Identifier Source: org_study_id