A Six-month Study to Compare Outcome Differences and Visceral Response ... Irritable Bowel Syndrome

NCT ID: NCT00368771

Last Updated: 2016-11-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

163 participants

Study Classification

INTERVENTIONAL

Study Start Date

2002-07-31

Study Completion Date

2010-05-31

Brief Summary

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The purpose of this study is to assess the effect of participation in one of the following interventions: (1) IBS Stress Management; (2) IBS Symptom Management; or (3) IBS Educational Training on improving IBS associated symptoms. It is anticipated that this research will provide information on the usefulness of psychological approaches in treating IBS and will help scientists better understand the disorder.

Detailed Description

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Conditions

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Irritable Bowel Syndrome

Keywords

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Irritable Bowel Syndrome Abdominal Pain Abdominal Discomfort Diarrhea Constipation IBS

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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1

IBS Stress Management

Group Type ACTIVE_COMPARATOR

IBS Stress Management

Intervention Type BEHAVIORAL

If randomly assigned to this intervention, the session with the therapist will consist of training about IBS symptoms and their relationship to stress, as well as skills training in relaxation and ways of identifying and challenging mistaken thoughts about life events. The goal of this treatment is to lessen mental and physical stressful reactions to daily events, and therefore lessen IBS symptoms as a reaction to stress. The patient will be encouraged to apply relaxation skills to stressful situations.

2

IBS Symptom Management

Group Type ACTIVE_COMPARATOR

IBS Symptom Management

Intervention Type BEHAVIORAL

If assigned to this group, the therapist will discuss feelings, over-attention to IBS symptoms, and your fear of IBS symptoms. Patients will learn how to identify thoughts that may increase your IBS symptoms and will practice how to change these thoughts to ones that make them feel more comfortable. The sessions will focus on reactions to daily life that in turn result in IBS Symptoms.

3

IBS Educational Training

Group Type ACTIVE_COMPARATOR

IBS Educational Training

Intervention Type BEHAVIORAL

Those assigned to this group will be given educational materials about IBS and will discuss the reading material with the therapist. The reading topics include information on gut disorders, anatomy and physiology of the gut, assessment procedures, and how to manage IBS symptoms. Sessions will also consist of weekly reviews of daily records and IBS symptoms. The goal of this intervention is to provide educational training about IBS.

Interventions

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IBS Stress Management

If randomly assigned to this intervention, the session with the therapist will consist of training about IBS symptoms and their relationship to stress, as well as skills training in relaxation and ways of identifying and challenging mistaken thoughts about life events. The goal of this treatment is to lessen mental and physical stressful reactions to daily events, and therefore lessen IBS symptoms as a reaction to stress. The patient will be encouraged to apply relaxation skills to stressful situations.

Intervention Type BEHAVIORAL

IBS Symptom Management

If assigned to this group, the therapist will discuss feelings, over-attention to IBS symptoms, and your fear of IBS symptoms. Patients will learn how to identify thoughts that may increase your IBS symptoms and will practice how to change these thoughts to ones that make them feel more comfortable. The sessions will focus on reactions to daily life that in turn result in IBS Symptoms.

Intervention Type BEHAVIORAL

IBS Educational Training

Those assigned to this group will be given educational materials about IBS and will discuss the reading material with the therapist. The reading topics include information on gut disorders, anatomy and physiology of the gut, assessment procedures, and how to manage IBS symptoms. Sessions will also consist of weekly reviews of daily records and IBS symptoms. The goal of this intervention is to provide educational training about IBS.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Irritable Bowel Syndrome

Exclusion Criteria

* GI pathology (organic disease) that affects bowel transit
* Co-morbid pain disorders
* Current or recent history (within 24 months) of drug or alcohol abuse
* Clinical evidence (including physical exam, laboratory tests) of significant medical disease that may interfere with the patient successfully completing the trial
* Planned use of drugs or agents that affect GI motility and/or perception
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Institute of Nursing Research (NINR)

NIH

Sponsor Role collaborator

University of California, Los Angeles

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Bruce D Naliboff, PhD

Role: PRINCIPAL_INVESTIGATOR

University of California Los Angeles, West Los Angeles VA Healthcare System

Michelle G Craske, PhD

Role: PRINCIPAL_INVESTIGATOR

University of California, Los Angeles

Countries

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United States

References

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Craske MG, Wolitzky-Taylor KB, Labus J, Wu S, Frese M, Mayer EA, Naliboff BD. A cognitive-behavioral treatment for irritable bowel syndrome using interoceptive exposure to visceral sensations. Behav Res Ther. 2011 Jun;49(6-7):413-21. doi: 10.1016/j.brat.2011.04.001. Epub 2011 Apr 19.

Reference Type RESULT
PMID: 21565328 (View on PubMed)

Related Links

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Other Identifiers

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R01NR007768

Identifier Type: NIH

Identifier Source: secondary_id

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DK-NR07768

Identifier Type: -

Identifier Source: secondary_id

R01NR007768

Identifier Type: NIH

Identifier Source: org_study_id

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