BNP Guided Care in Addition to Multidisciplinary Care

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Study Classification

INTERVENTIONAL

Study Start Date

2003-09-30

Study Completion Date

2005-09-30

Brief Summary

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HF is associated with repeated hospitalisations and poor prognosis.The aim of this study is to investigate whether BNP-guided care (BGC) in addition to multidisciplinary management(MM) improves outcome compared to HNC alone or usual care (UC) for decompensated HF patients after discharge.

Patients hospitalised with cardiac decompensation in 9 Viennese hospitals are randomised to BGC, MM alone, or UC. MM includes 2 consultations of a heart failure (HF) specialist 10 days and 2 months after discharge for recommending medical optimisation and care by a specialised HF nurse including 4 home visits and telephone contact. In addition, BGC includes intensified increase of medical treatment during repeated follow-up visits in a HF clinic in patients with an Nt-BNP level above 2200pg/ml at discharge.

Detailed Description

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Conditions

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Decompensated Heart Failure

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Blinding Strategy

NONE

Interventions

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BNP-guided care in addition to multidisciplinary management

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

1. Clinical signs and symptoms of cardiac decompensation during the present hospitalisation
2. NYHA class III or IV at time of admission
3. Cardiothoracic ratio \> 0.5, and/or left ventricular ejection fraction \<40% documented by echocardiography

Exclusion Criteria

\-

Minimum Eligible Age

19 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Principal Investigators

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Richard Pacher, MD

Role: PRINCIPAL_INVESTIGATOR

Medical University of Vienna

References

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Berger R, Moertl D, Peter S, Ahmadi R, Huelsmann M, Yamuti S, Wagner B, Pacher R. N-terminal pro-B-type natriuretic peptide-guided, intensive patient management in addition to multidisciplinary care in chronic heart failure a 3-arm, prospective, randomized pilot study. J Am Coll Cardiol. 2010 Feb 16;55(7):645-53. doi: 10.1016/j.jacc.2009.08.078.

Reference Type DERIVED

PMID: 20170790 (View on PubMed)

Other Identifiers

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VF: 05.05.2003

Identifier Type: -

Identifier Source: org_study_id