Chemoradiotherapy Followed by Surgery for Advanced Paranasal Sinus Cancer
NCT ID: NCT00347256
Last Updated: 2008-12-10
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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WITHDRAWN
NA
60 participants
INTERVENTIONAL
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NON_RANDOMIZED
SINGLE_GROUP
TREATMENT
NONE
Interventions
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cisplatin
targeted radiation therapy
tumor resection
Eligibility Criteria
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Inclusion Criteria
* Creatinin clearance \>= 50 ml/min or serum creatinine =\<1.5 mg/dl
* Total bilirubin, AST, ALT =\< 1.5 X laboratory uln
* ANC \>= 2000/mm3, platelets \>= 100,000/mm3
* Serum calcium within normal range
* T3 or T4 state tumors of paranasal sinuses
* Squamous cell carcinoma, adenocarcinoma, high-grade mucoepidermoid carcinoma, sinonasal undifferentiated carcinoma
Exclusion Criteria
* Other serious comorbidity that may significantly reduce the survival in next 5 years
* Pregnant or lactating women
* History of radiation to the head and neck region
* Paranasal sinus tumor is recurrent after prior treatment
* Presence of cervical node metastasis
* Presence of distant metastasis
* Advanced nasopharyngeal malignancy with sphenoid or posterior ethmoid invasion
18 Years
ALL
No
Sponsors
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North American Skull Base Society
OTHER
University of Tennessee
OTHER
Principal Investigators
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Sandeep Samant, MS, FRCS
Role: STUDY_CHAIR
University of Tennessee
Sandeep Samant, MS, FRCS
Role: PRINCIPAL_INVESTIGATOR
University of Tennessee
Related Links
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North American Skull Base Society webpage
Other Identifiers
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NASBS-PNS001
Identifier Type: -
Identifier Source: org_study_id
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