Fatigue in Multiple Sclerosis: Evaluated With 3 MRI and Transcranial Magnetic Stimulation
NCT ID: NCT00342381
Last Updated: 2007-12-17
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE2
120 participants
INTERVENTIONAL
2006-06-30
2007-12-31
Brief Summary
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Detailed Description
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Department of Neurology, Aarhus University Hospital, Denmark
Conditions
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Keywords
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Study Design
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RANDOMIZED
CROSSOVER
TREATMENT
DOUBLE
Study Groups
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3.4 diaminopyridine
Single dose 3,4 diaminopyridine
3,4-diaminopyridine
Single dose 3,4 diaminopyridine
Placebo
Two tablets identical to active treatment
Placebo
Single dose placebo treatment
Interventions
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3,4-diaminopyridine
Single dose 3,4 diaminopyridine
Placebo
Single dose placebo treatment
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* EDSS: max 3.5
* Right handed
* Normal function of the right hand
Exclusion Criteria
* Known dementia
* Drug or alcohol abuse
* Treatment with psychoactive drugs within one week before study entry
* Major changes of medical treatment within 3 weeks before study entry
* Attack within 4 weeks before study entry
* Pregnancy
* Conditions interfering with 3,4-diaminopyridine treatment
* Conditions interfering with MRI
* Conditions interfering with transcranial magnetic stimulation
18 Years
55 Years
ALL
Yes
Sponsors
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The Danish Multiple Sclerosis Society
UNKNOWN
University of Aarhus
OTHER
Responsible Party
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Dep of neurology, Aarhus University Hospital
Principal Investigators
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Henning Andersen, MD, DMSc
Role: PRINCIPAL_INVESTIGATOR
Aarhus University Hospital
Johannes Jacobsen, Professor
Role: STUDY_CHAIR
Aarhus University Hospital
Locations
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Aarhus University Hospital, Department of Neurology
Aarhus, , Denmark
Countries
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Other Identifiers
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20060003
Identifier Type: -
Identifier Source: org_study_id