Evaluation of the Efficacy and Safety of Laxymig® as Prophylactic Treatment in Patients With Migraine

NCT ID: NCT00334178

Last Updated: 2007-09-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

74 participants

Study Classification

INTERVENTIONAL

Study Start Date

2004-11-30

Study Completion Date

2006-09-30

Brief Summary

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The purpose of this study is to evaluate the efficacy and safety of Laxymig® ER compared with placebo in prophylactic monotherapy treatment of migraine headache.

Detailed Description

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The purpose of this study is to evaluate the efficacy and safety of Laxymig® ER compared with placebo in prophylactic monotherapy treatment of migraine headache.

Four weeks baseline, following with 12 weeks treatment phase. Subjects migraine are recorded by diary cards and re-evaluated by the investigator.

Subject will have visit every 4-week (+/- 7 days).

Conditions

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Migraine With Aura Migraine Without Aura

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Interventions

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Laxymig ER (drug)

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Clinical diagnosis of migraine with or without aura (typical aura with migraine headache)
* Subjects who had an average of two or more migraine frequencies per month during the 3 months before screening

Exclusion Criteria

* Female subjects who are pregnant, lactating
* Chronic daily headache
* Previous treatment with three or more migraine prophylaxis medications failed
* Subjects with hepatic disease whose liver enzymes are over 2 times of upper limit of reference or significant dysfunction
* Coexisting medical, neurological, or psychiatric disorder that may hinder the study according to the investigator's judgment
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Lotus Pharmaceutical

INDUSTRY

Sponsor Role lead

Principal Investigators

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Shuu-Jiun Wang, MD

Role: PRINCIPAL_INVESTIGATOR

Taipei Veterans General Hospital, Taiwan

Locations

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Changhua Christian Hospital

Changhua, , Taiwan

Site Status

Chung-Ho Memorial Hospital, Kaohsiung Medical University

Kaohsiung City, , Taiwan

Site Status

Chang-Gung Memorial Hospital

Linkou District, , Taiwan

Site Status

Chinese Medical University Hospital

Taichung, , Taiwan

Site Status

SinLau Christian Hospital

Tainan City, , Taiwan

Site Status

Taipei Veterans General Hospital

Taipei, , Taiwan

Site Status

Taipei Medical University Hospital

Taipei, , Taiwan

Site Status

Countries

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Taiwan

Other Identifiers

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LAXY-P001-R-2003

Identifier Type: -

Identifier Source: org_study_id