An Efficacy Study of a Single Dose Treatment of PRO-513 for Subjects Suffering a Migraine Attack

NCT ID: NCT00330850

Last Updated: 2007-04-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

650 participants

Study Classification

INTERVENTIONAL

Study Start Date

2006-05-31

Study Completion Date

2006-12-31

Brief Summary

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The purpose of the study is to show the efficacy of a single dose of PRO-513 for treating subjects suffering moderate pain form a migraine attack, with or without aura. The study is also intended to show the effectiveness of PRO-513 for associated symptoms of nausea, photophobia, and phonophobia due to a migraine attack.

Detailed Description

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Conditions

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Migraine Photophobia Phonophobia

Study Design

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Allocation Method

RANDOMIZED

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Interventions

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PRO-513

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Male and Female subjects
* 18-65 years of age
* Primary diagnosis of migraine attack with aura or migraine attack without aura
* Migraine history of averaging at least 1 migraine attack per month but averaging not more than 6 migraine attacks per month over the prior year
* Female subjects must use an effective form of birth control

Exclusion Criteria

* Excluding subjects with a history of other serious events causing secondary headaches
* Excluding subjects with a current medical condition that could interfere with the overall study intent or affect the absorption, distribution, metabolism, or excretion of the study medication
* Excluding subjects with a history or current medical condition that could confound the study results or use of a concomitant medication that could interfere with the study drug
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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ProEthic Pharmaceuticals

INDUSTRY

Sponsor Role lead

Principal Investigators

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Richard Lipton, MD

Role: PRINCIPAL_INVESTIGATOR

Montefiore Headache Center

Locations

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Associated Neurologists of Southern CT

Fairfield, Connecticut, United States

Site Status

New England Center for Headache

Stamford, Connecticut, United States

Site Status

LCFP Inc.

Fort Myers, Florida, United States

Site Status

Palm Beach Neurological Center

Palm Beach Gardens, Florida, United States

Site Status

Diamond Headache Clinic

Chicago, Illinois, United States

Site Status

International Research Center

Towson, Maryland, United States

Site Status

Michigan Head-Pain and Neurologic Institute

Ann Arbor, Michigan, United States

Site Status

Mercy Health Research

St Louis, Missouri, United States

Site Status

New York Headache Center

New York, New York, United States

Site Status

Headache Wellness Center

Greensboro, North Carolina, United States

Site Status

DermResearch, Inc.

Austin, Texas, United States

Site Status

J&S Studies, Inc.

Bryan, Texas, United States

Site Status

Houston Headache Clinic

Houston, Texas, United States

Site Status

Road Runner Research, Ltd.

San Antonio, Texas, United States

Site Status

The Innovative Clinical Research Center

Alexandria, Virginia, United States

Site Status

Advanced Healthcare, S.C.

Milwaukee, Wisconsin, United States

Site Status

Countries

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United States

Other Identifiers

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PRO-513301

Identifier Type: -

Identifier Source: org_study_id