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Impact of Patient-Prosthesis-Mismatch on Coronary Flow Reserve

NCT ID: NCT00310947

Last Updated: 2006-04-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

48 participants

Study Classification

OBSERVATIONAL

Study Start Date

2005-03-31

Study Completion Date

2006-01-31

Brief Summary

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Complete normalization of CFR following AVR for aortic stenosis was observed only for stentless valves. Besides the superior hemodynamic performance this might explain the excellent long term results of this valve design.

Detailed Description

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Conditions

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Coronary Artery Disease

Study Design

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Observational Model Type

NATURAL_HISTORY

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

Aortic valve stenosis

Exclusion Criteria

Coronary artery disease
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Medtronic

INDUSTRY

Sponsor Role collaborator

Johann Wolfgang Goethe University Hospital

OTHER

Sponsor Role lead

Principal Investigators

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Peter Kleine, MD,PhD

Role: PRINCIPAL_INVESTIGATOR

JW Goethe University Ffm

Locations

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JW Goethe University Ffm

Frankfurt am Main, Hesse, Germany

Site Status

Countries

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Germany

References

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Bakhtiary F, Schiemann M, Dzemali O, Dogan S, Schachinger V, Ackermann H, Moritz A, Kleine P. Impact of patient-prosthesis mismatch and aortic valve design on coronary flow reserve after aortic valve replacement. J Am Coll Cardiol. 2007 Feb 20;49(7):790-6. doi: 10.1016/j.jacc.2006.10.052. Epub 2007 Feb 5.

Reference Type DERIVED
PMID: 17306709 (View on PubMed)

Other Identifiers

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Coronary flow reserve

Identifier Type: -

Identifier Source: org_study_id