Study Comparing Pitavastatin and Atorvastatin in Patients With Type II Diabetes Mellitus and Combined Dyslipidemia

NCT ID: NCT00309751

Last Updated: 2010-02-23

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

View full results

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

418 participants

Study Classification

INTERVENTIONAL

Study Start Date

2005-12-31

Study Completion Date

2007-06-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of this study is to compare the efficacy and safety of pitavastatin with that of atorvastatin in patients with type II diabetes mellitus (type II DM) and combined dyslipidemia.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Type II Diabetes Mellitus Dyslipidemia

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Pitavastatin 4 mg QD

Pitavastatin 4 mg once daily

Group Type EXPERIMENTAL

Pitavastatin

Intervention Type DRUG

Pitavastatin 4 mg QD

Atorvastatin 20 mg QD

Atorvastatin 20 mg once daily

Group Type ACTIVE_COMPARATOR

Atorvastatin

Intervention Type DRUG

Atorvastatin 20 mg

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Pitavastatin

Pitavastatin 4 mg QD

Intervention Type DRUG

Atorvastatin

Atorvastatin 20 mg

Intervention Type DRUG

Other Intervention Names

Discover alternative or legacy names that may be used to describe the listed interventions across different sources.

Lipitor

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Males and females (ages 18-75 years)
* Type II DM treated with oral anti-diabetic medication (sulfonylurea, metformin, glitazones, or combination therapy)
* Must have been following a restrictive diet
* Diagnosis of combined dyslipidemia

Exclusion Criteria

* Homozygous familial hypercholesterolemia
* Conditions which may cause secondary dyslipidemia
* Uncontrolled diabetes mellitus
* Abnormal pancreatic, liver, or renal function
* Abnormal serum creatine kinase (CK) above the pre-specified level
* Significant heart disease
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Kowa Research Europe

INDUSTRY

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Kowa Research Europe

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Dragos Budinski, Med Dr.

Role: STUDY_DIRECTOR

Kowa Research Europe

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

CCBR Aalborg

Aalborg, , Denmark

Site Status

CCBR A/S

Ballerup Municipality, , Denmark

Site Status

CCBR Vejle

Vejle, , Denmark

Site Status

Gemeinschaftspraxis am Bahnhof

Berlin-Spandau, , Germany

Site Status

Pharmakologisches Studienzentum Chemnitz

Chemnitz, , Germany

Site Status

Internistische Diabetische Schwerpunktpraxis Dr.

Frankfurt am Main, , Germany

Site Status

Internistische Gemeinschaftspraxis

Mainz, , Germany

Site Status

Gemeinschaftspraxis Dr. Senftleber, Dr. Kohler

Messkirch, , Germany

Site Status

Bhagwan Mahaveer Jain Heart Centre

Bangalore, , India

Site Status

Sri Ramachandra Medical College Hospital

Chennai, , India

Site Status

Apollo Hospitals

Hyderabaad, , India

Site Status

CARE Group of Hospitals

Hyderabaad, , India

Site Status

PD Hinduja Hospital

Mumbai, , India

Site Status

Andromed Breda

Breda, , Netherlands

Site Status

Andromed Eindhoven

Eindhoven, , Netherlands

Site Status

Andromed Noord

Groningen, , Netherlands

Site Status

Andromed Leiden

Leiden, , Netherlands

Site Status

Andromed Nijmegen

Nijmegen, , Netherlands

Site Status

Andromed Rotterdam

Rotterdam, , Netherlands

Site Status

Andromed Oost

Velp, , Netherlands

Site Status

Andromed Zoetermeer

Zoetermeer, , Netherlands

Site Status

Podlaski Osrodek Kardiologii

Bialystok, , Poland

Site Status

NZOZ GCP Dobra Praktyka Lekaska

Gruziadz, , Poland

Site Status

NZOZ Terapia Optima

Katowice, , Poland

Site Status

NZOZ Centrum, Poradnia Kardiologiczna

Siedlce, , Poland

Site Status

Spec. Gab. Lek. Internistyczno-Kardiologicznly

Tarnów, , Poland

Site Status

Woj.Szp.Spec.Nr 1 im. Prof. J. Gasinskiego

Tychy, , Poland

Site Status

Instytut Zywnosci i Zywienia

Warsaw, , Poland

Site Status

Lecznica PROSEN SMO

Warsaw, , Poland

Site Status

Szpital Wolski,im. Dr A. Gostynskiej

Warsaw, , Poland

Site Status

NZOZ Esculap, Przychodnia Lekary Rodzinnych

Łosice, , Poland

Site Status

Synexus Reading Clinical Research Centre

Berkshire, , United Kingdom

Site Status

Synexus Lancashire Clinical Research Centre

Lancashire, , United Kingdom

Site Status

Synexus Merseyside Clinical Research Centre

Liverpool, , United Kingdom

Site Status

Synexus Manchester Clinical Research Centre

Manchester, , United Kingdom

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Denmark Germany India Netherlands Poland United Kingdom

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

NK-104-305

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Teneligliptin and Atorvastatin DDI Study
NCT03769870 COMPLETED PHASE1