Constraint-induced Movement Therapy (CIMT) and Bimanual Training (HABIT) in Children With Hemiplegic Cerebral Palsy

NCT ID: NCT00305006

Last Updated: 2021-06-01

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

42 participants

Study Classification

INTERVENTIONAL

Study Start Date

2007-07-31

Study Completion Date

2011-02-28

Brief Summary

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A randomized control trial of bimanual training. The protocols have been developed at Columbia University to be child friendly and draws upon our experience since 1997 with constraint-induced movement therapy in children with cerebral palsy.

Detailed Description

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A new treatment involving bimanual (Hand-Arm Bimanual Intensive Therapy (HABIT). The protocols have been developed at Columbia University to be child friendly and draws upon our experience since 1998 with constraint-induced movement therapy in children with cerebral palsy. The interventions are performed in a 15 day day-camp setting with several children and at least one therapist per child. We have conducted 24 day camps to date since 2002, and are now collaborating with clinicians worldwide to expand our treatment availability. The aim is to promote the use of and improve the coordination of movement of both hands together. PARTICIPATION IS FREE. Please check out our website for more information: http://www.tc.edu/centers/cit/.

Conditions

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Cerebral Palsy Hemiplegia Children Pediatric

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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CIMT Intervention

Participants randomized to this arm were provided with 90 minutes of Constraint-Induced Movement Therapy (CIMT), which requires hand restraint and progression of unimanual tasks.

Group Type EXPERIMENTAL

Constraint-Induced Movement Therapy (CIMT)

Intervention Type PROCEDURE

90 hours

HABIT Intervention

Participants randomized to this arm were provided with 90 minutes of Hand-Arm Bimanual Intensive Therapy (HABIT), which requires that tasks are progressed bimanually.

Group Type EXPERIMENTAL

Hand-Arm Bimanual Intensive Therapy (HABIT)

Intervention Type PROCEDURE

90 hours

Interventions

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Constraint-Induced Movement Therapy (CIMT)

90 hours

Intervention Type PROCEDURE

Hand-Arm Bimanual Intensive Therapy (HABIT)

90 hours

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

willingness to agree to intervention and testing procedures and travel to the University for participation and testing.

Exclusion Criteria

* health problems not associated with CP
* uncontrollable seizures
* visual problems that would interfere with carrying out the intervention or testing
* botulinum toxin therapy in the upper extremity musculature during the last six months or who wish to receive it within the period of study
Minimum Eligible Age

30 Months

Maximum Eligible Age

14 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Thrasher Research Fund

OTHER

Sponsor Role collaborator

Emory University

OTHER

Sponsor Role collaborator

Teachers College, Columbia University

OTHER

Sponsor Role lead

Responsible Party

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Andrew Gordon

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Andrew M Gordon, Ph.D.

Role: PRINCIPAL_INVESTIGATOR

Columbia University

Locations

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Teachers College, Columbia University

New York, New York, United States

Site Status

Countries

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United States

References

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Charles J, Gordon AM. Development of hand-arm bimanual intensive training (HABIT) for improving bimanual coordination in children with hemiplegic cerebral palsy. Dev Med Child Neurol. 2006 Nov;48(11):931-6. doi: 10.1017/S0012162206002039.

Reference Type BACKGROUND
PMID: 17044964 (View on PubMed)

Charles JR, Wolf SL, Schneider JA, Gordon AM. Efficacy of a child-friendly form of constraint-induced movement therapy in hemiplegic cerebral palsy: a randomized control trial. Dev Med Child Neurol. 2006 Aug;48(8):635-42. doi: 10.1017/S0012162206001356.

Reference Type BACKGROUND
PMID: 16836774 (View on PubMed)

Gordon AM, Charles J, Wolf SL. Efficacy of constraint-induced movement therapy on involved upper-extremity use in children with hemiplegic cerebral palsy is not age-dependent. Pediatrics. 2006 Mar;117(3):e363-73. doi: 10.1542/peds.2005-1009.

Reference Type BACKGROUND
PMID: 16510616 (View on PubMed)

Gordon AM, Schneider JA, Chinnan A, Charles JR. Efficacy of a hand-arm bimanual intensive therapy (HABIT) in children with hemiplegic cerebral palsy: a randomized control trial. Dev Med Child Neurol. 2007 Nov;49(11):830-8. doi: 10.1111/j.1469-8749.2007.00830.x.

Reference Type BACKGROUND
PMID: 17979861 (View on PubMed)

Steenbergen B, Charles J, Gordon AM. Fingertip force control during bimanual object lifting in hemiplegic cerebral palsy. Exp Brain Res. 2008 Mar;186(2):191-201. doi: 10.1007/s00221-007-1223-6. Epub 2008 Jan 26.

Reference Type BACKGROUND
PMID: 18224309 (View on PubMed)

Schertz M, Gordon AM. Changing the model: a call for a re-examination of intervention approaches and translational research in children with developmental disabilities. Dev Med Child Neurol. 2009 Jan;51(1):6-7. doi: 10.1111/j.1469-8749.2008.03220.x. No abstract available.

Reference Type BACKGROUND
PMID: 19087099 (View on PubMed)

Gordon AM, Chinnan A, Gill S, Petra E, Hung YC, Charles J. Both constraint-induced movement therapy and bimanual training lead to improved performance of upper extremity function in children with hemiplegia. Dev Med Child Neurol. 2008 Dec;50(12):957-8. doi: 10.1111/j.1469-8749.2008.03166.x. No abstract available.

Reference Type BACKGROUND
PMID: 19160464 (View on PubMed)

Hung YC, Casertano L, Hillman A, Gordon AM. The effect of intensive bimanual training on coordination of the hands in children with congenital hemiplegia. Res Dev Disabil. 2011 Nov-Dec;32(6):2724-31. doi: 10.1016/j.ridd.2011.05.038. Epub 2011 Jun 28.

Reference Type BACKGROUND
PMID: 21715141 (View on PubMed)

Gordon AM, Hung YC, Brandao M, Ferre CL, Kuo HC, Friel K, Petra E, Chinnan A, Charles JR. Bimanual training and constraint-induced movement therapy in children with hemiplegic cerebral palsy: a randomized trial. Neurorehabil Neural Repair. 2011 Oct;25(8):692-702. doi: 10.1177/1545968311402508. Epub 2011 Jun 23.

Reference Type RESULT
PMID: 21700924 (View on PubMed)

Related Links

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http://www.tc.edu/centers/cit/

Center for cerebral palsy research

Other Identifiers

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08126

Identifier Type: -

Identifier Source: org_study_id

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