Rapid Diagnostic Testing and Artemisinin-Based Combination Therapy for Uncomplicated Malaria by Community Health Workers
NCT ID: NCT00301015
Last Updated: 2007-11-01
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE4
3005 participants
INTERVENTIONAL
2006-03-31
2006-08-31
Brief Summary
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The hypothesis is that rapid diagnostic tests used by community health workers will reduce the use of antimalarial drugs (Coartem; Novartis) by 30% without affecting the health outcome.
Detailed Description
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Conditions
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Study Design
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RANDOMIZED
CROSSOVER
DIAGNOSTIC
NONE
Study Groups
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1
Malaria diagnosis aided with rapid diagnostic test
Rapid diagnostic test for malaria
We used Paracheck Pf® (Orchid Biomedical Systems, India) as rapid diagnostic test in this trial
2
Malaria diagnosis based on clinical judgement only
Rapid diagnostic test for malaria
We used Paracheck Pf® (Orchid Biomedical Systems, India) as rapid diagnostic test in this trial
Interventions
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Rapid diagnostic test for malaria
We used Paracheck Pf® (Orchid Biomedical Systems, India) as rapid diagnostic test in this trial
Eligibility Criteria
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Inclusion Criteria
* Informed consent
Exclusion Criteria
* Pregnancy
* Previous enrollment in the study within the last 28 days
ALL
No
Sponsors
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Muhimbili University of Health and Allied Sciences
OTHER
Karolinska University Hospital
OTHER
Principal Investigators
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Anders Björkman, MD, PhD
Role: STUDY_DIRECTOR
Dept of Medicine, Karolinska University Hospital, 171 76 Stockholm, Sweden
Locations
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Villages
Kibaha, Kibaha District, Tanzania
Countries
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References
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Mubi M, Janson A, Warsame M, Martensson A, Kallander K, Petzold MG, Ngasala B, Maganga G, Gustafsson LL, Massele A, Tomson G, Premji Z, Bjorkman A. Malaria rapid testing by community health workers is effective and safe for targeting malaria treatment: randomised cross-over trial in Tanzania. PLoS One. 2011;6(7):e19753. doi: 10.1371/journal.pone.0019753. Epub 2011 Jul 5.
Other Identifiers
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RapAct 28-02-2006
Identifier Type: -
Identifier Source: org_study_id