Effect of Whole Body Vibration on Bone and Fall Related Parameters

NCT ID: NCT00292916

Last Updated: 2015-05-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

PHASE3

Total Enrollment

150 participants

Study Classification

INTERVENTIONAL

Study Start Date

2006-01-31

Study Completion Date

2007-07-31

Brief Summary

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The effect of whole body vibration (WBV) on bone strength and fall frequency in older adults is still vague. Although there is some evidence that WBV may impact Bone Mineral Density in very frail elderly, there is a lack of data concerning the effect of WBV in community-living elderly woman. We hypothesize that WBV significantly affects bone parameters as assessed by DXA, QCT, US and bone markers with parallel positive changes of fall related risk factors (power, strength, balance, and reaction time). We further hypothesize that the effects of WBV were superior to conventional resistance exercise.

Detailed Description

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Conditions

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Atrophy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

SINGLE

Interventions

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whole body vibration

Intervention Type BEHAVIORAL

resistance exercise

Intervention Type BEHAVIORAL

"wellness"

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* community living elderly females \>/=65 years
* live expectation \> 2 years

Exclusion Criteria

* secondary osteoporosis
* CVD-events including stroke
* participation in other studies
* medication and illness affecting bone metabolism within the last 2 years
* medication with impact on falls
* low physical performance (\<50 Watt during ergometry)
* excessive alcohol-intake
Minimum Eligible Age

65 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Institute of Biometrie and Medical Statistics

UNKNOWN

Sponsor Role collaborator

Netzwerk-Knochengesundheit

UNKNOWN

Sponsor Role collaborator

Siemens-Betriebskrankenkasse

INDUSTRY

Sponsor Role collaborator

University of Erlangen-Nürnberg Medical School

OTHER

Sponsor Role lead

Responsible Party

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Wolfgang Kemmler

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Willi A Kalender, PhD

Role: STUDY_CHAIR

University of Erlangen-Nürnberg Medical School

Locations

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Institute of Medical Physics

Erlangen, , Germany

Site Status

Countries

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Germany

References

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Kemmler W, Engelke K, Baumann H, Beeskow C, von Stengel S, Weineck J, Kalender WA. Bone status in elite male runners. Eur J Appl Physiol. 2006 Jan;96(1):78-85. doi: 10.1007/s00421-005-0060-1. Epub 2005 Oct 26.

Reference Type BACKGROUND
PMID: 16307280 (View on PubMed)

Engelke K, Kemmler W, Lauber D, Beeskow C, Pintag R, Kalender WA. Exercise maintains bone density at spine and hip EFOPS: a 3-year longitudinal study in early postmenopausal women. Osteoporos Int. 2006 Jan;17(1):133-42. doi: 10.1007/s00198-005-1938-9. Epub 2005 Aug 12.

Reference Type BACKGROUND
PMID: 16096715 (View on PubMed)

Stengel SV, Kemmler W, Pintag R, Beeskow C, Weineck J, Lauber D, Kalender WA, Engelke K. Power training is more effective than strength training for maintaining bone mineral density in postmenopausal women. J Appl Physiol (1985). 2005 Jul;99(1):181-8. doi: 10.1152/japplphysiol.01260.2004. Epub 2005 Mar 3.

Reference Type BACKGROUND
PMID: 15746294 (View on PubMed)

Kemmler W, Weineck J, Kalender WA, Engelke K. The effect of habitual physical activity, non-athletic exercise, muscle strength, and VO2max on bone mineral density is rather low in early postmenopausal osteopenic women. J Musculoskelet Neuronal Interact. 2004 Sep;4(3):325-34.

Reference Type BACKGROUND
PMID: 15615501 (View on PubMed)

Von Stengel S, Kemmler W, Bebenek M, Engelke K, Kalender WA. Effects of whole-body vibration training on different devices on bone mineral density. Med Sci Sports Exerc. 2011 Jun;43(6):1071-9. doi: 10.1249/MSS.0b013e318202f3d3.

Reference Type DERIVED
PMID: 20980923 (View on PubMed)

Other Identifiers

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D-ER-OFZ-200501-Vib

Identifier Type: -

Identifier Source: org_study_id

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