Trial Outcomes & Findings for A Registry for Comparing Catheter-Related Infection Rates Among Various Shunt Systems in the Treatment of Hydrocephalus (NCT NCT00280904)

NCT ID: NCT00280904

Last Updated: 2013-03-08

Results Overview

Number of shunt infections occurring in subjects implanted with antibiotic impregnated catheters and standard catheters.

Recruitment status

COMPLETED

Target enrollment

433 participants

Primary outcome timeframe

Implantation to Explant

Results posted on

2013-03-08

Participant Flow

Participant milestones

Participant milestones
Measure
Ventriculoperitoneal Shunt Patients
Patients receiving a de novo standard or antibiotic (AI) catheter implant or catheter replacement of a prior ventriculoperitoneal shunt.
Overall Study
STARTED
433
Overall Study
COMPLETED
433
Overall Study
NOT COMPLETED
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

A Registry for Comparing Catheter-Related Infection Rates Among Various Shunt Systems in the Treatment of Hydrocephalus

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Ventriculoperitoneal Shunt Patients
n=433 Participants
Patients receiving a de novo standard or antibiotic (AI) catheter implant or catheter replacement of a prior ventriculoperitoneal shunt.
Age, Categorical
<=18 years
183 Participants
n=5 Participants
Age, Categorical
Between 18 and 65 years
193 Participants
n=5 Participants
Age, Categorical
>=65 years
57 Participants
n=5 Participants
Age Continuous
31.3 years
STANDARD_DEVIATION 25.49 • n=5 Participants
Sex: Female, Male
Female
194 Participants
n=5 Participants
Sex: Female, Male
Male
239 Participants
n=5 Participants

PRIMARY outcome

Timeframe: Implantation to Explant

Number of shunt infections occurring in subjects implanted with antibiotic impregnated catheters and standard catheters.

Outcome measures

Outcome measures
Measure
Ventriculoperitoneal Shunt Patients
n=433 Participants
Patients receiving a de novo antibiotic impregnated(AI)or standard catheter implant or catheter replacement of a prior ventriculoperitoneal shunt.
Number of Subjects With Shunt Infections
14 participants

SECONDARY outcome

Timeframe: April 2008

Outcome measures

Outcome measures
Measure
Ventriculoperitoneal Shunt Patients
n=433 Participants
Patients receiving a de novo antibiotic impregnated(AI)or standard catheter implant or catheter replacement of a prior ventriculoperitoneal shunt.
Non-infectious Antibiotic Impregnated (AI) and Standard Catheter Subjects With Shunt Failures
40 participants

Adverse Events

Ventriculoperitoneal Shunt Patients

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

J. Thomas Megerian

Codman & Shurtleff

Phone: 1-508-828-8274

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place

Restriction type: LTE60