Study on Safety and Efficacy of an Oral Contraceptive in Treating Acne Papulopustulosa

NCT ID: NCT00280657

Last Updated: 2023-06-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

1326 participants

Study Classification

INTERVENTIONAL

Study Start Date

2004-03-10

Study Completion Date

2005-05-21

Brief Summary

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The purpose of the study is to determine safety and efficacy of an oral contraceptive in treating acne papulopustulosa.

Detailed Description

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The study has previously been posted by Schering AG, Germany. Schering AG, Germany has been renamed to Bayer Schering Pharma AG, Germany.Bayer Schering Pharma AG, Germany is the sponsor of the trial.

Conditions

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Acne Vulgaris

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Arm 1

Group Type EXPERIMENTAL

Valette

Intervention Type DRUG

1 tablet 0.030 mg ethinylestradiol / 2 mg dienogest + 1 placebo tablet daily for 21 days followed by a 7-day tablet-free interval, oral administration for 6 cycles

Arm 2

Group Type ACTIVE_COMPARATOR

Diane

Intervention Type DRUG

1 tablet 0.035 mg ethinylestradiol / 2 mg cyproterone acetate + 1 placebo tablet daily for 21 days followed by a 7-day tablet-free interval, oral administration for 6 cycles

Arm 3

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type DRUG

2 placebo tablets daily for 21 days followed by a 7-day tablet-free interval, oral administration for 6 cycles

Interventions

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Valette

1 tablet 0.030 mg ethinylestradiol / 2 mg dienogest + 1 placebo tablet daily for 21 days followed by a 7-day tablet-free interval, oral administration for 6 cycles

Intervention Type DRUG

Diane

1 tablet 0.035 mg ethinylestradiol / 2 mg cyproterone acetate + 1 placebo tablet daily for 21 days followed by a 7-day tablet-free interval, oral administration for 6 cycles

Intervention Type DRUG

Placebo

2 placebo tablets daily for 21 days followed by a 7-day tablet-free interval, oral administration for 6 cycles

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Patients with mild to moderate facial papulopustular acne

Exclusion Criteria

* Contraindication against use of hormonal contraceptives
Minimum Eligible Age

16 Years

Maximum Eligible Age

45 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Bayer

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Bayer Study Director

Role: STUDY_DIRECTOR

Bayer

Locations

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Chomutov, , Czechia

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Čáslav, , Czechia

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Kutná Hora, , Czechia

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Louny, , Czechia

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Olomouc, , Czechia

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Prague, , Czechia

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Prague, , Czechia

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Slaný, , Czechia

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Svitavy, , Czechia

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Ústí nad Labem, , Czechia

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Grudziądz, , Poland

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Lodz, , Poland

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Lublin, , Poland

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Poznan, , Poland

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Warsaw, , Poland

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Warsaw, , Poland

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Warsaw, , Poland

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Warsaw, , Poland

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Wroclaw, , Poland

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Korolyov, , Russia

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Moscow, , Russia

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Moscow, , Russia

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Moscow, , Russia

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Moscow, , Russia

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Moscow, , Russia

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Moscow, , Russia

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Moskva, , Russia

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Moskva, , Russia

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Petrozavodsk, , Russia

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Saint Petersburg, , Russia

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Saint Petersburg, , Russia

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Saint Petersburg, , Russia

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Saint Petersburg, , Russia

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Saint Petersburg, , Russia

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Saint Petersburg, , Russia

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Saint Petersburg, , Russia

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Saint Petersburg, , Russia

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Saint Petersburg, , Russia

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Banská Bystrica, , Slovakia

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Bratislava, , Slovakia

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Kosice-Saca, , Slovakia

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Košice, , Slovakia

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Nitra, , Slovakia

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Alchevs'k, , Ukraine

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Chernivtsi, , Ukraine

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Dnipropetrovsk, , Ukraine

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Donetsk, , Ukraine

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Ivano-Frankivsk, , Ukraine

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Kharkiv, , Ukraine

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Kiev, , Ukraine

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Kiev, , Ukraine

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Kyiv, , Ukraine

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Luhansk, , Ukraine

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Lviv, , Ukraine

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Makiivka, , Ukraine

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Odesa, , Ukraine

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Poltava, , Ukraine

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Rivne, , Ukraine

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Simferopol, , Ukraine

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Ternopil, , Ukraine

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Uzhhorod, , Ukraine

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Zaporizhzhia, , Ukraine

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Countries

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Czechia Poland Russia Slovakia Ukraine

Other Identifiers

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307760

Identifier Type: -

Identifier Source: secondary_id

91299

Identifier Type: -

Identifier Source: org_study_id

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