Comparison of Femoral Versus Jugular Routes for Temporary Hemodialysis in Seriously Ill Patients

NCT ID: NCT00277888

Last Updated: 2014-11-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

750 participants

Study Classification

INTERVENTIONAL

Study Start Date

2004-04-30

Study Completion Date

2007-05-31

Brief Summary

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The purpose of this study is to determine whether a jugular route leads to a lower rate of complications as compared with a femoral route for catheterization in patients admitted in several intensive care units in France who develop acute renal failure requiring hemodiafiltration or hemodialysis.

Detailed Description

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Conditions

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Kidney Failure, Acute Critical Illness

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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Femoral route

Group Type EXPERIMENTAL

Femoral route for hemodialysis

Intervention Type PROCEDURE

Jugular route

Group Type EXPERIMENTAL

Jugular route for hemodialysis

Intervention Type PROCEDURE

Interventions

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Femoral route for hemodialysis

Intervention Type PROCEDURE

Jugular route for hemodialysis

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Admitted in intensive care unit (ICU)
* Requiring hemodialysis
* Clinicians have the choice between jugular and femoral routes

Exclusion Criteria

* Chronic renal failure requiring long term dialysis
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Caen

OTHER

Sponsor Role lead

Principal Investigators

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Jean-Jacques Parienti, MD

Role: PRINCIPAL_INVESTIGATOR

University Hospital, Caen

Locations

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Medical and nephrologic Intensive Care Unit, CHU Amien Sud

Amiens, , France

Site Status

CH Argenteuil

Argenteuil, , France

Site Status

Medical Intensive Care Unit, CHU de Caen

Caen, , France

Site Status

Surgical Intensive Care Unit

Caen, , France

Site Status

CHU de Clermont Ferrand

Clermont-Ferrand, , France

Site Status

CHU Raymond Pointcarré

Garches, , France

Site Status

Hôpital Cochin

Paris, , France

Site Status

Hôpital Lariboisière

Paris, , France

Site Status

Hôpital St Joseph

Paris, , France

Site Status

CH Saint Malo

St-Malo, , France

Site Status

Countries

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France

References

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Parienti JJ, Thirion M, Megarbane B, Souweine B, Ouchikhe A, Polito A, Forel JM, Marque S, Misset B, Airapetian N, Daurel C, Mira JP, Ramakers M, du Cheyron D, Le Coutour X, Daubin C, Charbonneau P; Members of the Cathedia Study Group. Femoral vs jugular venous catheterization and risk of nosocomial events in adults requiring acute renal replacement therapy: a randomized controlled trial. JAMA. 2008 May 28;299(20):2413-22. doi: 10.1001/jama.299.20.2413.

Reference Type RESULT
PMID: 18505951 (View on PubMed)

Parienti JJ, Megarbane B, Fischer MO, Lautrette A, Gazui N, Marin N, Hanouz JL, Ramakers M, Daubin C, Mira JP, Charbonneau P, du Cheyron D; Cathedia Study Group. Catheter dysfunction and dialysis performance according to vascular access among 736 critically ill adults requiring renal replacement therapy: a randomized controlled study. Crit Care Med. 2010 Apr;38(4):1118-25. doi: 10.1097/CCM.0b013e3181d454b3.

Reference Type RESULT
PMID: 20154599 (View on PubMed)

Parienti JJ, Dugue AE, Daurel C, Mira JP, Megarbane B, Mermel LA, Daubin C, du Cheyron D; Members of the Cathedia Study Group. Continuous renal replacement therapy may increase the risk of catheter infection. Clin J Am Soc Nephrol. 2010 Aug;5(8):1489-96. doi: 10.2215/CJN.02130310. Epub 2010 Jun 17.

Reference Type RESULT
PMID: 20558562 (View on PubMed)

Dugue AE, Levesque SP, Fischer MO, Souweine B, Mira JP, Megarbane B, Daubin C, du Cheyron D, Parienti JJ; Cathedia Study Group. Vascular access sites for acute renal replacement in intensive care units. Clin J Am Soc Nephrol. 2012 Jan;7(1):70-7. doi: 10.2215/CJN.06570711. Epub 2011 Nov 10.

Reference Type RESULT
PMID: 22076877 (View on PubMed)

Parienti JJ, Deryckere S, Megarbane B, Valette X, Seguin A, Sauneuf B, Mira JP, Souweine B, Cattoir V, Daubin C, du Cheyron D; Cathedia Study Group. Quasi-experimental study of sodium citrate locks and the risk of acute hemodialysis catheter infection among critically ill patients. Antimicrob Agents Chemother. 2014 Oct;58(10):5666-72. doi: 10.1128/AAC.03079-14. Epub 2014 Jun 30.

Reference Type RESULT
PMID: 24982071 (View on PubMed)

Iachkine J, Buetti N, de Grooth HJ, Briant AR, Mimoz O, Megarbane B, Mira JP, Ruckly S, Souweine B, du Cheyron D, Mermel LA, Timsit JF, Parienti JJ. Development and validation of a multivariable prediction model of central venous catheter-tip colonization in a cohort of five randomized trials. Crit Care. 2022 Jul 7;26(1):205. doi: 10.1186/s13054-022-04078-x.

Reference Type DERIVED
PMID: 35799302 (View on PubMed)

Tsujimoto Y, Miki S, Shimada H, Tsujimoto H, Yasuda H, Kataoka Y, Fujii T. Non-pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal replacement therapy. Cochrane Database Syst Rev. 2021 Sep 14;9(9):CD013330. doi: 10.1002/14651858.CD013330.pub2.

Reference Type DERIVED
PMID: 34519356 (View on PubMed)

Related Links

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http://www.cdc.gov/mmwr/PDF/rr/rr5110.pdf

Guidelines for the prevention of intravascular catheter-related infections

Other Identifiers

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PHRC-Cathedia

Identifier Type: -

Identifier Source: org_study_id