Comparing Two Instrumentation Systems for the Treatment of Adolescent Scoliosis

NCT ID: NCT00273598

Last Updated: 2017-10-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE2

Total Enrollment

126 participants

Study Classification

INTERVENTIONAL

Study Start Date

1997-09-30

Study Completion Date

2002-09-30

Brief Summary

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Idiopathic scoliosis affects 2-5% of adolescents. This study will compare the quality of life, functional outcome, cosmetic result, and the correction of spinal deformity of two instrumentation systems for the treatment of adolescent idiopathic scoliosis.

Detailed Description

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Conditions

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Scoliosis

Keywords

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Scoliosis spinal disease pediatrics Adolescents Universal Spinal Instrumentation System Moss Miami Spinal Instrumentation System Orthopedic Surgery

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Interventions

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Moss Miami Spine Instrumentation System

Intervention Type PROCEDURE

Universal Spine Instrumentation System

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Age 8-18 years
* Diagnosis of idiopathic scoliosis requiring posterior instrumentation and fusion(including those also requiring anterior release with or without anterior instrumentation) who could receive either the USS or the Moss Miami system
* Patients with scoliosis and an incidental finding of conus \< L1-2 disc level, provided they have no symptoms or signs
* Patients with scoliosis and an incidental finding of a small syrinx (provided the syrinx is non-progressive and does not require neurosurgical treatment)
* Patients with non-progressive spondylolysis

Exclusion Criteria

* Spinal cord abnormalities with any neurologic symptoms or signs
* Spinal cord lesions requiring neurosurgical interventions, such as hydromyelia requiring Arnold Chiari decompression
* Primary muscle diseases, such as muscular dystrophy
* Neurologic diseases (e.g. Charcot-Marie Tooth, Guillain-Barre syndrome, cerebral palsy, or spina bifida, etc.)
* Primary abnormalities of bones(e.g. osteogenesis imperfecta)
* Congenital scoliosis
Minimum Eligible Age

8 Years

Maximum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Canadian Institutes of Health Research (CIHR)

OTHER_GOV

Sponsor Role collaborator

Synthes Canada

INDUSTRY

Sponsor Role collaborator

DePuy-Acromed, Inc.

INDUSTRY

Sponsor Role collaborator

Johnson & Johnson

INDUSTRY

Sponsor Role collaborator

The Hospital for Sick Children

OTHER

Sponsor Role lead

Responsible Party

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James Wright

Surgeon-in-Chief & Chief of Perioperative Services

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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James G Wright, MD

Role: PRINCIPAL_INVESTIGATOR

The Hospital for Sick Children, Toronto Canada

Locations

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The Hospital for Sick Children

Toronto, Ontario, Canada

Site Status

Countries

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Canada

References

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Wright JG, Donaldson S, Howard A, Stephens D, Alman B, Hedden D. Are surgeons' preferences for instrumentation related to patient outcomes? A randomized clinical trial of two implants for idiopathic scoliosis. J Bone Joint Surg Am. 2007 Dec;89(12):2684-93. doi: 10.2106/JBJS.F.00720.

Reference Type BACKGROUND
PMID: 18056501 (View on PubMed)

Other Identifiers

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0019970040

Identifier Type: -

Identifier Source: org_study_id