Cosopt Versus Xalatan

NCT ID: NCT00273429

Last Updated: 2007-01-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Study Classification

INTERVENTIONAL

Study Start Date

2005-04-30

Study Completion Date

2005-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

To compare the 24-hour efficacy and safety, measured every three hours, of the dorzolamide/timolol fixed combination given twice daily versus latanoprost and placebo each given once daily.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Open-Angle Glaucoma Ocular Hypertension

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

timolol maleate 0.5%

Intervention Type DRUG

dorzolamide/timolol maleate fixed combination

Intervention Type DRUG

latanoprost 0.005%

Intervention Type DRUG

placebo

Intervention Type DRUG

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* adults with primary open-angle, pigmentary, or exfoliation glaucoma, or ocular hypertenstion
* intraocular pressure should be 22 to 30 mm Hg inclusive on timolol BID at the 08:00 H
* ETDRS visual acuity must be 1.0 or better in both eyes

Exclusion Criteria

* any contraindications to study medications
* any anticipated change in systemic hypertensive therapy during the trial
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Pharmaceutical Research Network

OTHER

Sponsor Role lead

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

William C. Stewart, MD

Role: STUDY_DIRECTOR

Pharmaceutical Research Network, LLC

Jay Mulaney, MD

Role: PRINCIPAL_INVESTIGATOR

Central Florida Eye Associates

Sriram Sonty, MD, FACS

Role: PRINCIPAL_INVESTIGATOR

Midwest Eye Center SC

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Central Florida Eye Associates

Lakeland, Florida, United States

Site Status

Midwest Eye Center SC

Bourbonnais, Illinois, United States

Site Status

Countries

Review the countries where the study has at least one active or historical site.

United States

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

PRN 04-015

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Lumigan Versus Cosopt
NCT00273455 COMPLETED PHASE4