The Molecular Mechanism and the Role of NRAMP 1gene on Tuberculosis in Taiwan Aboriginal Tribes Population

NCT ID: NCT00266383

Last Updated: 2005-12-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

250 participants

Study Classification

OBSERVATIONAL

Study Start Date

2005-01-31

Study Completion Date

2005-12-31

Brief Summary

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The human homologue of mice natural-resistance-associated macrophage protein 1 (Nramp 1) gene, NRAMP 1, has been reported to play a role in the susceptibility to tuberculosis in humans. The aboriginal population in Taiwan has a 5-fold higher prevalence of tuberculosis than the Han Chinese. Whether genetic factors such as NRAMP 1 polymorphisms play a role in the prevalence of tuberculosis in Taiwanese aboriginals should be clarified.

Detailed Description

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Conditions

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Tuberculosis

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

OTHER

Eligibility Criteria

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Inclusion Criteria

* The NRAMP 1 polymorphism of tuberculous patients in Taiwan.

Exclusion Criteria

\-
Minimum Eligible Age

0 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Health Research Institutes, Taiwan

OTHER

Sponsor Role lead

Principal Investigators

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Ih-Jen Su, M.D., Ph.D.

Role: PRINCIPAL_INVESTIGATOR

Division of Clinical Research, National Health Research Institutes

Locations

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National Health Research Institutes

Miaoli County, , Taiwan

Site Status

Countries

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Taiwan

Other Identifiers

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DOH94-DC-1009

Identifier Type: -

Identifier Source: org_study_id