Observation of Patients With Primary Pulmonary Hypertension Receiving Prescribed Ventavis Inhalation Therapy Regarding Safety and Efficacy for up to 4 Years

NCT ID: NCT00250640

Last Updated: 2015-02-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

106 participants

Study Classification

OBSERVATIONAL

Study Start Date

2005-04-30

Study Completion Date

2012-07-31

Brief Summary

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This is an observational study to monitor the continued effectiveness of Ventavis (inhaled iloprost) in the long-term. The study observes the effects and the safety of Ventavis inhalation therapy over at least 2 years and up to 4 years. A total of 54 patients from around 30 study sites in Europe will be included in the study. This observational study will collect information in patients receiving a medication that is already available on prescription in the participating countries. Ventavis is used to treat moderate cases of primary pulmonary hypertension.

Detailed Description

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Conditions

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Hypertension, Pulmonary

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Group 1

Iloprost (Ventavis, BAYQ6256)

Intervention Type DRUG

The recommended dose is 2.5 micrograms or 5.0 micrograms of inhaled iloprost (as delivered at the mouthpiece of the nebuliser). Dosing should follow the recommendations of the current package leaflet

Interventions

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Iloprost (Ventavis, BAYQ6256)

The recommended dose is 2.5 micrograms or 5.0 micrograms of inhaled iloprost (as delivered at the mouthpiece of the nebuliser). Dosing should follow the recommendations of the current package leaflet

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* The treating physician has chosen Ventavis as a suitable long-term treatment for the patient
* Patient with primary pulmonary hypertension (i.e. Idiopathic Pulmonary Arterial Hypertension or Familial Pulmonary Arterial Hypertension) and classified as NYHA functional class III (NYHA = New York Heart Association)
* No prior treatment with Ventavis or other active treatments for primary pulmonary hypertension within 6 weeks of date of study inclusion (unless otherwise advised by Bayer Schering Pharma)

Exclusion Criteria

* Any condition that prevents participation in the study, including pregnancy and other contraindications for Ventavis treatment (as listed in the current Ventavis Summary of Product Characteristics and patient package insert)
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Bayer

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Bayer Study Director

Role: STUDY_DIRECTOR

Bayer

Locations

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Brest, , France

Site Status

Clamart, , France

Site Status

Lille, , France

Site Status

Lyon, , France

Site Status

Pessac, , France

Site Status

Reims, , France

Site Status

Strasbourg, , France

Site Status

Vandœuvre-lès-Nancy, , France

Site Status

Donaueschingen, Baden-Wurttemberg, Germany

Site Status

Heidelberg, Baden-Wurttemberg, Germany

Site Status

Heidelberg, Baden-Wurttemberg, Germany

Site Status

Löwenstein, Baden-Wurttemberg, Germany

Site Status

Erlangen, Bavaria, Germany

Site Status

München, Bavaria, Germany

Site Status

München, Bavaria, Germany

Site Status

Regensburg, Bavaria, Germany

Site Status

Hamburg, City state of Hamburg, Germany

Site Status

Giessen, Hesse, Germany

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Bonn, North Rhine-Westphalia, Germany

Site Status

Cologne, North Rhine-Westphalia, Germany

Site Status

Essen, North Rhine-Westphalia, Germany

Site Status

Mönchengladbach, North Rhine-Westphalia, Germany

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Wuppertal, North Rhine-Westphalia, Germany

Site Status

Homburg/Saar, Saarland, Germany

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Dresden, Saxony, Germany

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Leipzig, Saxony, Germany

Site Status

Berlin, State of Berlin, Germany

Site Status

Berlin, State of Berlin, Germany

Site Status

Erfurt, Thuringia, Germany

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Bologna, , Italy

Site Status

Pavia, , Italy

Site Status

Pisa, , Italy

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Roma, , Italy

Site Status

Coimbra, Coimbra District, Portugal

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Lisbon, , Portugal

Site Status

Barcelona, Barcelona, Spain

Site Status

Córdoba, Córdoba, Spain

Site Status

Barcelona, , Spain

Site Status

Madrid, , Spain

Site Status

Glasgow, , United Kingdom

Site Status

London, , United Kingdom

Site Status

Newcastle upon Tyne, , United Kingdom

Site Status

Sheffield, , United Kingdom

Site Status

Countries

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France Germany Italy Portugal Spain United Kingdom

Other Identifiers

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308120

Identifier Type: OTHER

Identifier Source: secondary_id

91430

Identifier Type: -

Identifier Source: org_study_id

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