Trial Outcomes & Findings for Post-Traumatic Brain Injury (Post-TBI) Fatigue and Its Treatment (NCT NCT00233090)

NCT ID: NCT00233090

Last Updated: 2016-04-15

Results Overview

Self-report of fatigue

Recruitment status

TERMINATED

Study phase

PHASE2

Target enrollment

21 participants

Primary outcome timeframe

comparison pre and post treatment

Results posted on

2016-04-15

Participant Flow

Participant milestones

Participant milestones
Measure
Modafinil
single dose of 200 mg. a day of modafinil for four weeks
Placebo
daily dose of placebo for four weeks
Overall Study
STARTED
12
9
Overall Study
COMPLETED
12
9
Overall Study
NOT COMPLETED
0
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Post-Traumatic Brain Injury (Post-TBI) Fatigue and Its Treatment

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Modafinil
n=12 Participants
single dose of 200 mg. a day of modafinil for four weeks
Placebo
n=9 Participants
daily dose of placebo for four weeks
Total
n=21 Participants
Total of all reporting groups
Age, Continuous
52 years
STANDARD_DEVIATION 12 • n=5 Participants
54 years
STANDARD_DEVIATION 13 • n=7 Participants
53 years
STANDARD_DEVIATION 12 • n=5 Participants
Sex: Female, Male
Female
8 Participants
n=5 Participants
3 Participants
n=7 Participants
11 Participants
n=5 Participants
Sex: Female, Male
Male
4 Participants
n=5 Participants
6 Participants
n=7 Participants
10 Participants
n=5 Participants
Region of Enrollment
United States
12 participants
n=5 Participants
9 participants
n=7 Participants
21 participants
n=5 Participants

PRIMARY outcome

Timeframe: comparison pre and post treatment

Population: Study terminated due to low enrollment. data was not analyzed and is no longer available for analysis. Data not kept electronically and study records are no longer available.

Self-report of fatigue

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: comparison pre and post treatment

Population: Study terminated due to low enrollment. data was not analyzed and is no longer available for analysis. Data not kept electronically and study records are no longer available.

Cognitive performance

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: comparison pre and post treatment

Population: Study terminated due to low enrollment. data was not analyzed and is no longer available for analysis. Data not kept electronically and study records are no longer available.

mood

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: comparison pre and post treatment

Population: Study terminated due to low enrollment. data was not analyzed and is no longer available for analysis. Data not kept electronically and study records are no longer available.

pain

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: comparison pre and post treatment

Population: Study terminated due to low enrollment. data was not analyzed and is no longer available for analysis. Data not kept electronically and study records are no longer available.

sleep quality

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: comparison pre and post treatment

Population: Study terminated due to low enrollment. data was not analyzed and is no longer available for analysis. Data not kept electronically and study records are no longer available.

health status

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: comparison pre and post treatment

Population: Study terminated due to low enrollment. data was not analyzed and is no longer available for analysis. Data not kept electronically and study records are no longer available.

participation

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: comparison pre and post treatment

Population: Study terminated due to low enrollment. data was not analyzed and is no longer available for analysis. Data not kept electronically and study records are no longer available.

quality of life

Outcome measures

Outcome data not reported

Adverse Events

Modafinil

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Placebo

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Wayne A Gordon, PhD

Icahn School of Medicine at Mount Sinai

Phone: 212-659-9372

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place