PiCCO Guided Therapy in Liver Cirrhosis

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2005-08-31

Study Completion Date

2007-08-31

Brief Summary

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Prospective comparison of standard therapy in liver cirrhosis versus standard therapy plus intensified hemodynamic monitoring using the PiCCO system.

Detailed Description

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Patients presenting with advanced liver cirrhosis will receive either standard treatment or standard treatment plus hemodynamic monitoring with the PiCCO device. Fluids and vasoacitve drugs will be administered according to the measurements over a period of 5 days.

Conditions

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Liver Cirrhosis

Keywords

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Liver cirrhosis Hemodynamics Fluid balance

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Interventions

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Hemodynamic monitoring system PiCCO

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Liver cirrhosis Child-Pugh-Score \> 7
* Ascites \> 500 ml

Exclusion Criteria

* Coronary heart disease
* Apoplexia \< 6 months ago
* Vasculitis
* Thrombosis
* Arterial occlusive disease \> stadium II

Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Principal Investigators

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Jens Encke, PD Dr. med.

Role: PRINCIPAL_INVESTIGATOR

Heidelberg University

Locations

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University of Heidelberg, Clinical center

Heidelberg, , Germany

Site Status

Countries

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Germany

Other Identifiers

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PiCCO

Identifier Type: -

Identifier Source: org_study_id