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Characterization of the Use of Antipsychotics in PTSD During the Past Seven Years

NCT ID: NCT00230893

Last Updated: 2006-09-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

99 participants

Study Classification

OBSERVATIONAL

Study Start Date

2005-07-31

Study Completion Date

2005-09-30

Brief Summary

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The primary objective is to examine the percentage of patients with PTSD who were prescribed an antipsychotic over the past seven years in the VA Network 7 (AL, GA, SC) and compare the percentage on an annual basis. We will also determine the type and dose of antipsychotics received. We hypothesize that there has been a significant increase in antipsychotic use, especially atypical antipsychotics, prescribed for patients with PTSD over the last 7 years

Detailed Description

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This study is a retrospective electronic review of the VISN 7 Data Warehouse to determine what have been the emerging trends in prescriptions of atypical antipsychotic medications over the past seven years for the treatment of posttraumatic stress disorder (PTSD) in the VA

This study is a retrospective electronic review of patients of the VISN 7 Data Warehouse of patients with a diagnosis of PTSD treated with antipsychotics as monotherapy or adjunctive therapy at a VA Medical Center or VA clinic in VISN 7 (GA, SC, and AL). The data will be retrieved from a computerized list of patients treated in VA VISN 7 for PTSD from 1998-2005 and cross-referenced with the electronic pharmacy file for having received a prescription of an antipsychotic medication. No personal identifiers will be collected. The data will then be examined to determine what type of antipsychotics were prescribed and the dose and duration of the antipsychotics. In addition, demographics and clinical characteristics available through the Data Warehouse will be collected.

Conditions

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PTSD Post-Traumatic Stress Disorder

Keywords

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Antipsychotics PTSD Post Traumatic Stress Disorder monotherapy adjunct therapy

Study Design

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Observational Model Type

DEFINED_POPULATION

Study Time Perspective

RETROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Male or female patients, any race or ethnic origin at least 19 years of age.
* Patients with a diagnosis of PTSD
* Treated with an antipsychotic as a monotherapy or adjunctive therapy
* Patient must have been seen at a VA medical center or clinic within VISN 7 during the study period.

Exclusion Criteria

* Patients not diagnosed with PTSD
* Not treated with an antipsychotic as a monotherapy or adjunctive therapy
* Patients outside of Network 7
* Patients with a diagnosis of schizophrenia, schizoaffective disorder, or bipolar disorder
Minimum Eligible Age

19 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Janssen, LP

INDUSTRY

Sponsor Role collaborator

Tuscaloosa Research & Education Advancement Corporation

OTHER

Sponsor Role lead

Principal Investigators

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Lori L. Davis, MD

Role: PRINCIPAL_INVESTIGATOR

Tuscaloosa Veterans Affairs Medical Center

Locations

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Tuscaloosa VA Medical Center

Tuscaloosa, Alabama, United States

Site Status

Countries

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United States

References

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Kozaric-Kovacic D, Pivac N, Muck-Seler D, Rothbaum BO. Risperidone in psychotic combat-related posttraumatic stress disorder: an open trial. J Clin Psychiatry. 2005 Jul;66(7):922-7. doi: 10.4088/jcp.v66n0716.

Reference Type BACKGROUND
PMID: 16013909 (View on PubMed)

Other Identifiers

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TREAC - PTSD Retrospective

Identifier Type: -

Identifier Source: secondary_id

TREAC - PTSD Retrospective

Identifier Type: -

Identifier Source: org_study_id