Effect of Paroxetine on COAT-Platelet Production in Normal Volunteers and Patients With Cardiovascular Disease
NCT ID: NCT00229528
Last Updated: 2008-09-22
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
COMPLETED
PHASE4
25 participants
INTERVENTIONAL
2004-03-31
2006-05-31
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
PACT (Platelet Activity After Clopidogrel Termination)
NCT00619073
Different Platelet Activities Between Intracoronary and Peripheral Blood in Coronary Artery Disease Patients
NCT03078257
Clinical Management of Antiplatelet Drug Resistance in Patients With Drug Eluting Coronary Stents
NCT00589862
Appraisal of MDCO-157 and Plavix® Pharmacokinetics and Pharmacodynamics in Healthy Volunteers With an Evaluation
NCT01860105
Platelet Function Monitoring in Patients Treated With Clopidogrel at the Time of Primary Percutaneous Coronary Angioplasty
NCT00827346
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
NON_RANDOMIZED
PARALLEL
PREVENTION
NONE
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
Paxil-CR
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* patients with heart disease
* between ages 18 \& 65
Exclusion Criteria
* adults greater than 65 years
* those who can not keep appointments
* patients within 2 weeks of a coronary catheterization
* patients within 6 months of unstable angina or myocardial infarction
* individuals with allergies to paroxetine or similar medications
* individuals having adverse events to paroxetine or similar medications
* individuals with diagnosis of mania
* individuals with a diagnosis of hypomania
* individuals with a diagnosis of bipolar disorders
* individuals with a diagnosis of depression
* individuals with a diagnosis of panic disorders
* individuals with a diagnosis of seizure disorders
* individuals with a history of suicide attempts
* individuals with a diagnosis of hyponatremia
* individuals with active bleeding disorders
* individuals with a diagnosis of narrow angle glaucoma
* individuals with an estimated creatinine clearance of less that 30 ml/min
* individuals taking potentially interacting medications
18 Years
65 Years
ALL
Yes
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
GlaxoSmithKline
INDUSTRY
University of Oklahoma
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
University of Oklahoma Dept of Pharmacy
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
Stephen F. Hamilton, Pharm.D.
Role: PRINCIPAL_INVESTIGATOR
The University of Oklahoma College of Pharmacy
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
The University of Oklahoma Health Sciences Center
Oklahoma City, Oklahoma, United States
Countries
Review the countries where the study has at least one active or historical site.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
1000774
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.