Hypercoagulable Parameters as Predictors of Thrombotic Events and Prognosis in Patients With Advanced Non-Small Cell Lung Carcinoma

NCT ID: NCT00192829

Last Updated: 2007-04-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2005-06-30

Brief Summary

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The association between cancer and thrombosis is well known and the occurrence of thrombotic complications is commonly associated with poor prognosis. The aim os this study is to determine the possible value of hypercoagulable parameters as prognostic parameters in advanced non-small cell lung carcinoma (NSCLC).

Detailed Description

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Conditions

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Non-Small Cell Lung Carcinoma Venous Thromboembolism

Study Design

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Study Time Perspective

PROSPECTIVE

Interventions

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Blood sample withdrawal

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Histologically or cytologically confirmed diagnosis of NSCLC.
* normal serum bilirubin
* informed concent to participate in the study

Exclusion Criteria

* anticoagulant therapy
* infectious disease
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Rambam Health Care Campus

OTHER

Sponsor Role lead

Principal Investigators

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Galit Sarig, Ph.D

Role: PRINCIPAL_INVESTIGATOR

Rambam Health Care Campus

Locations

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Hematology Laboratory

Haifa, , Israel

Site Status RECRUITING

Oncology Institution, Rambam Health Campus

Haifa, , Israel

Site Status RECRUITING

Countries

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Israel

Central Contacts

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Galit Sarig, Ph.D

Role: CONTACT

+972-4-8543503

Nissim Haim, M.D

Role: CONTACT

Facility Contacts

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Galit Sarig, Ph.D

Role: primary

+972-4-8543523

Nissim Haim, M.D

Role: primary

References

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Haim N, Lanir N, Hoffman R, Haim A, Tsalik M, Brenner B. Acquired activated protein C resistance is common in cancer patients and is associated with venous thromboembolism. Am J Med. 2001 Feb 1;110(2):91-6. doi: 10.1016/s0002-9343(00)00691-4.

Reference Type BACKGROUND
PMID: 11165549 (View on PubMed)

Blom JW, Osanto S, Rosendaal FR. The risk of a venous thrombotic event in lung cancer patients: higher risk for adenocarcinoma than squamous cell carcinoma. J Thromb Haemost. 2004 Oct;2(10):1760-5. doi: 10.1111/j.1538-7836.2004.00928.x.

Reference Type BACKGROUND
PMID: 15456487 (View on PubMed)

Ferrigno D, Buccheri G, Ricca I. Prognostic significance of blood coagulation tests in lung cancer. Eur Respir J. 2001 Apr;17(4):667-73. doi: 10.1183/09031936.01.17406670.

Reference Type BACKGROUND
PMID: 11401062 (View on PubMed)

Other Identifiers

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Thrombosis and cancer.CTIL

Identifier Type: -

Identifier Source: org_study_id