Growth Hormone and Heart Failure

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Total Enrollment

180 participants

Study Classification

OBSERVATIONAL

Study Start Date

2000-09-30

Study Completion Date

2003-02-28

Brief Summary

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Heart failure induces modification in several neurohormonal systems. The aim of this study is to determine if the growth hormone/IGF1 axis is modified in heart failure patients compared to healthy volunteers.

Detailed Description

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One hundred and sixty three heart failure patients were evaluated by clinical examination, echocardiography, exercise test and measurement of blood BNP. Growth hormone and IGF-1 plasma levels were determined in each patient. The same biological measurements were performed in a group of 148 healthy controls. Comparisons were performed between groups for Growth hormone plasma level, IGF-1 plasma level and Growth hormone/IGF-1 index. A correlation between the severity of heart failure and the different biological parameters was searched.

Conditions

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Heart Failure, Congestive

Keywords

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heart failure hormones growth substances

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

OTHER

Eligibility Criteria

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Inclusion Criteria

* Heart failure patients in stable condition

Exclusion Criteria

* cancer
* pituitary disease

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Principal Investigators

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Patrick Maison, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

APHP

Other Identifiers

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CRC00007

Identifier Type: -

Identifier Source: org_study_id