High Dose Chemotherapy and Allogeneic Hematopoietic Cell Transplant for Non-Hodgkin's Lymphoma

NCT ID: NCT00186394

Last Updated: 2010-07-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE2

Total Enrollment

35 participants

Study Classification

INTERVENTIONAL

Study Start Date

2000-04-30

Study Completion Date

2006-12-31

Brief Summary

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To evaluate the role of allogeneic hematopoietic cell transplantation in the treatment of NHL.

Detailed Description

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To determine safety and toxicity of a regimen of high dose chemotherapy with allogeneic peripheral blood progenitor cell transplantation; determine the efficacy of the procedure by following clinical outcomes and quality of life measures; and evaluate graft versus host disease incidence and severity with regimen.

Conditions

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Lymphoma, Non-Hodgkin Blood and Marrow Transplant (BMT) Lymphomas: Non-Hodgkin

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Interventions

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ablative allogeneic hematopoietic cell transplantation

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

Age: \>18 and \<61 years of age

Exclusion Criteria

Serum creatinine of \> 2 mg/dl or creatinine clearance \< 60 ml/min

Diseases other than non-Hodgkin's lymphoma

Prior bone marrow transplant procedure

Severe psychological or medical illness
Minimum Eligible Age

18 Years

Maximum Eligible Age

61 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Institutes of Health (NIH)

NIH

Sponsor Role collaborator

Stanford University

OTHER

Sponsor Role lead

Responsible Party

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Stanford University School of Medicine

Principal Investigators

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Wen-Kai Weng

Role: PRINCIPAL_INVESTIGATOR

Stanford University

Locations

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Stanford University School of Medicine

Stanford, California, United States

Site Status

Countries

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United States

Other Identifiers

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76679

Identifier Type: -

Identifier Source: secondary_id

BMT4L

Identifier Type: -

Identifier Source: secondary_id

NCT00186394

Identifier Type: -

Identifier Source: secondary_id

BMT4L

Identifier Type: -

Identifier Source: org_study_id

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