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Effect of Deep Brain Stimulation on Depression and Quality of Life in Parkinson's Patients

NCT ID: NCT00179101

Last Updated: 2006-08-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

42 participants

Study Classification

OBSERVATIONAL

Study Start Date

2004-04-30

Study Completion Date

2005-11-30

Brief Summary

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We will evaluate the effect of deep brain stimulation on the depression and quality of life in Parkinson's disease. We aim to compare depression pre-operatively and post-operatively in Parkinson's patients with deep brain stimulation to Parkinson's patients evaluated and approved for deep brain stimulation but who did not complete surgery. We will also compare quality of life measures between patients with and without deep brain stimulation.

Detailed Description

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Deep brain stimulation is an approved therapy for Parkinson's patients, and this procedure is actively performed at Vanderbilt University Hospital. Questions have been raised concerning the effect of deep brain stimulation on the depression commonly seen in Parkinson's patients. Through this study, we plan to evaluate and compare the incidence and severity of depression in Parkinson's patients with deep brain stimulation to those who did not complete the surgery. Primary literature has indicated a general increase in quality of life of those patients receiving DBS, but no studies have compared these two specific patient populations.

Conditions

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Parkinson's Disease

Keywords

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Parkinson's Disease Depression Quality of Life Deep Brain Stimulation

Study Design

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Observational Model Type

DEFINED_POPULATION

Study Time Perspective

OTHER

Interventions

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Deep Brain Stimulation

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Patients diagnosed with idiopathic Parkinson's disease.
* Patients who have received neuropsychological testing in preparation for possible deep brain stimulation.
* Patients are within the age of 50 and 85.

Exclusion Criteria

* Parkinson's patients not approved for deep brain stimulation on the basis of neuropsychological testing.
* Patients who received deep brain stimulation less than a year ago.
* Patients who do not consent to the study procedures.
Minimum Eligible Age

50 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Vanderbilt University

OTHER

Sponsor Role lead

Principal Investigators

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Courtney R Schadt, BS

Role: PRINCIPAL_INVESTIGATOR

Vanderbilt University

David Charles, MD

Role: STUDY_DIRECTOR

Vanderbilt University

Locations

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Vanderbilt University

Nashville, Tennessee, United States

Site Status

Countries

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United States

Other Identifiers

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040251

Identifier Type: -

Identifier Source: org_study_id