Effects of Local Anesthetic or Saline Solution on Peripheral Nerve Stimulation

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

TERMINATED

Clinical Phase

PHASE4

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2004-01-31

Study Completion Date

2005-01-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

In this study we want to examine the effect of a small amount of local anesthetic or saline solution on nerve conduction using a peripheral nerve stimulator.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Using electrical nerve stimulation in performing peripheral nerve helps to control the needle position in relation to the nerve and therefore may increase the likelihood of a successful nerve block. Defining the minimal stimulating current accepted also may help to avoid direct contact between nerve and needle or accidental endoneural injection and subsequent nerve lesion.

In recent years there have been many reports where several nerves, parts thereof or plexuses have been anesthetised using a multiple injection approach. That is, nerves in close proximity of each other have been subsequently blocked after using a nerve stimulator to locate them.

It is not clear though, whether a nerve may already be partially anesthetised in this situation and whether that would impair the correct use of a peripheral nerve stimulator.

The aim of this study is to examine the excitability of a peripheral nerve after injecting a small amount of local anesthetic agent or saline solution into the proximity of the nerve.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Percutaneous Electric Nerve Stimulation

Keywords

Explore important study keywords that can help with search, categorization, and topic discovery.

peripheral nerve stimulation saline local anesthestics regional anesthestia nerve damage

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

peripheral nerve stimulation (procedure)

Intervention Type PROCEDURE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

ASA 1-2

Exclusion Criteria

peripheral neuropathy, ASA \>2

Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Heinz Kaiser, MD

Role: STUDY_CHAIR

Rechbergklinik Bretten

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Rechbergklinik

Bretten, Baden-Wurttemberg, Germany

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Germany

References

Explore related publications, articles, or registry entries linked to this study.

Neuburger M, Gultlinger O, Ass B, Buttner J, Kaiser H. [Influence of blockades with local anesthetics on the stimulation ability of a nerve by peripheral nerve stimulation. Results of a randomized study]. Anaesthesist. 2005 Jun;54(6):575-7. doi: 10.1007/s00101-005-0824-3. German.

Reference Type RESULT

PMID: 15739091 (View on PubMed)

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

nervstim001

Identifier Type: -

Identifier Source: org_study_id

Effects of Local Anesthetic or Saline Solution on Peripheral Nerve Stimulation - a Randomised Study