Perception and Attitude Toward Estrogen Therapy Among Surgically Menopausal Women

NCT ID: NCT00173550

Last Updated: 2007-01-23

Basic Information

• Recruitment Status: UNKNOWN
• Total Enrollment: 200 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2004-08-31

Brief Summary

The aim of this study is to survey patient's cognition and attitude about health-related quality of life, use of estrogen, experience of menopausal syndrome, compliance of medication, experience, and satisfaction for women who underwent hysterectomy and bilateral oophorectomy before menopause.

Detailed Description

The cognition and attitude of menopausal women toward hormone replacement could have been changed since the report from WHI in July 2002. Previously, many women used hormone replacement to prevent cardiovascular disease and osteoporosis. Recently, the use has been challenged, exaggerated, and also discussed both in media press and academic meetings. Many women dare not to use them. The women who underwent hysterectomy and bilateral salpingo-oophorectomy before menopause may immediately face the problems caused by deficiency of female sex hormone. For this group of women, as yet there is no conclusion about whether the women should take hormone replacement therapy for a long time to osteoporosis, cardiovascular disease and other chronic disease. The arm for this study from WHI is not closed yet. While the women in our area might have been influenced by this report and have changed their mind. It is essential for us to make a clear understanding about the cognition and attitude for hormone replacement therapy for women who underwent hysterectomy and bilateral salpingo- oophorectomy. Therefore, it may be a pioneer study and worthwhile to do this study. Data from a medical center from 2000 to 2004 will be examined for evidence of bilateral oophorectomy & hysterectomy. The cause for the surgery will be confirmed by pathological findings. These women who were under 50 years of age will be candidate of the study. The women will be interviewed about their beliefs, and cognition, regarding their quality of life and health risks as well as their opinion on menopause and hormone replacement therapy.

Conditions

Menopause, Premature; Hysterectomy; Ovariectomy; Estrogen Replacement Therapy; Attitude; Perception

Study Design

• Observational Model Type: DEFINED_POPULATION
• Study Time Perspective: OTHER

Interventions

Hysterectomy and Bilateral salpingo-oophorectomy

Intervention Type: PROCEDURE

Eligibility Criteria

Inclusion Criteria

• Age under 50
• Hysterectomy and bilateral oophorectomy

Exclusion Criteria

• Unwilling to answer the questionnaires

• Minimum Eligible Age: 20 Years
• Maximum Eligible Age: 50 Years
• Eligible Sex: FEMALE
• Accepts Healthy Volunteers: No

Sponsors

National Science and Technology Council, Taiwan

OTHER_GOV

Sponsor Role: collaborator

National Taiwan University Hospital

OTHER

Sponsor Role: lead

Principal Investigators

Ruey-Jien Chen, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Department or Obstetrics and Gynecology, National Taiwan university Hospital

Locations

National Taiwan University Hospital Department of Obstetrics and Gynecology

Taipei, Taipei, Taiwan

Site Status: RECRUITING

Countries

Taiwan

Central Contacts

Ruey-Jien Chen, MD, PhD

Role: CONTACT

rjchen@ha.mc.ntu.edu.tw

886-2-23123456 ext. 5158

Facility Contacts

Ruey-Jien Chen, MD, PhD

Role: primary

rjchen@ha.c.ntu.edu.tw

886-2-2312-3456 ext. 5158

References

Anderson GL, Limacher M, Assaf AR, Bassford T, Beresford SA, Black H, Bonds D, Brunner R, Brzyski R, Caan B, Chlebowski R, Curb D, Gass M, Hays J, Heiss G, Hendrix S, Howard BV, Hsia J, Hubbell A, Jackson R, Johnson KC, Judd H, Kotchen JM, Kuller L, LaCroix AZ, Lane D, Langer RD, Lasser N, Lewis CE, Manson J, Margolis K, Ockene J, O'Sullivan MJ, Phillips L, Prentice RL, Ritenbaugh C, Robbins J, Rossouw JE, Sarto G, Stefanick ML, Van Horn L, Wactawski-Wende J, Wallace R, Wassertheil-Smoller S; Women's Health Initiative Steering Committee. Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: the Women's Health Initiative randomized controlled trial. JAMA. 2004 Apr 14;291(14):1701-12. doi: 10.1001/jama.291.14.1701.

Reference Type: BACKGROUND

PMID: 15082697 (View on PubMed)

Levens E, Williams RS. Current opinions and understandings of menopausal women about hormone replacement therapy (HRT)-the University of Florida experience. Am J Obstet Gynecol. 2004 Aug;191(2):641-6; discussion 646-7. doi: 10.1016/j.ajog.2004.06.074.

Reference Type: BACKGROUND

PMID: 15343254 (View on PubMed)

Related Links

http://ntuml.mc.ntu.edu.tw

library of National taiwan University Hospital

Other Identifiers

NSC93-2314-B-002-162

Identifier Type: -

Identifier Source: secondary_id

9461700710

Identifier Type: -

Identifier Source: org_study_id