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Effect of Cyclic Tensional Force on Osteogenic Differentiation of Human Periodontal Ligament Stem Cells

NCT ID: NCT00172744

Last Updated: 2007-10-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

20 participants

Study Classification

OBSERVATIONAL

Study Start Date

2005-04-30

Study Completion Date

2006-07-31

Brief Summary

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The purpose of this study is to observe cyclic tensional force on the osteogenic differentiation of human periodontal ligament stem cells.

Detailed Description

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This study is to investigate the effect of the cyclic mechanical strain on the osteogenic differentiation of mesenchymal stem cells. Mesenchymal stem cells will be cultured from the periodontal ligament tissue of the premolars extracted due to orthodontic reason.

Conditions

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Healthy

Keywords

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stem cells periodontal cells mechanical stress differentiation periodontal ligament

Study Design

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Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Orthodontic patients who need to have premolars extracted
Minimum Eligible Age

13 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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National Taiwan University Hospital

OTHER

Sponsor Role lead

Principal Investigators

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Yi-Jane Chen, MSD

Role: PRINCIPAL_INVESTIGATOR

School of Dentistry, College of Medicine, National Taiwan University

Locations

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School of Dentistry, College of Medicine, National Taiwan University

Taipei, , Taiwan

Site Status TERMINATED

School of Dentistry, College of Medicine, National Taiwan University

Taipei, , Taiwan

Site Status RECRUITING

Countries

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Taiwan

Central Contacts

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Yi-Jane Chen, MSD

Role: CONTACT

Phone: 886-2-23123456

Email: [email protected]

Facility Contacts

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Yi-Jane Chen, MSD

Role: primary

Other Identifiers

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9361701291

Identifier Type: -

Identifier Source: org_study_id