The Effect of a Weight Management Program During Treatment With Olanzapine

NCT ID: NCT00169702

Last Updated: 2008-01-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2003-06-30

Study Completion Date

2007-07-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The study is a prospective, randomized, open-label study.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

The principal objective of this trial is to investigate the effect of a comprehensive behavioural treatment program on weight gain in schizophrenic patients under olanzapine treatment, and on subjective well-being.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Schizophrenia

Keywords

Explore important study keywords that can help with search, categorization, and topic discovery.

Schizophrenia, weight management programme

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Standard

standard information

Group Type OTHER

weight management program

Intervention Type BEHAVIORAL

12 sessions, psychoeducation

weight management program

Intervention Type BEHAVIORAL

2 weekly, 12 sessions, psychoeducational weight management

Intervention

weight management program, 12 sessions, 2 weekly, psychoeducational program, interactive topics like healthy food, diet behavior, physical activity, stress reduction.

Group Type ACTIVE_COMPARATOR

weight management program

Intervention Type BEHAVIORAL

12 sessions, psychoeducation

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

weight management program

12 sessions, psychoeducation

Intervention Type BEHAVIORAL

weight management program

2 weekly, 12 sessions, psychoeducational weight management

Intervention Type BEHAVIORAL

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) criteria for schizophrenia
* Ages between 18 and 65
* Informed consent
* Weight gain of at least 1.5 kg in the first 4 weeks
* A sufficient understanding to participate adequately in the weight management program
* Patients must agree to cooperate with all tests and examinations required by the protocol.
* Each patient must understand the nature of the study and must sign an informed consent document.

Exclusion Criteria

* Serious, unstable somatic illnesses
* Illnesses associated with weight gain including renal and endocrine diseases
* Weight change greater than 3 kg in the preceding three months
* Weight gain less than 1.5 kg in the first 4 weeks
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Eli Lilly and Company

INDUSTRY

Sponsor Role collaborator

Else Kröner-Fresenius-Centre for Nutritional Medicine

UNKNOWN

Sponsor Role collaborator

Technical University of Munich

OTHER

Sponsor Role collaborator

Heinrich-Heine University, Duesseldorf

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Heinrich-Heine University

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Joachim Cordes, MD

Role: PRINCIPAL_INVESTIGATOR

Department of Psychiatry and Psychotherapy at the Heinrich-Heine-University Düsseldorf, Rhineland State Clinics Düsseldorf, Bergische Landstrasse 2, 40629 Düsseldorf, Germany

Ansgar Klimke, Prof

Role: STUDY_DIRECTOR

Department of Psychiatry, Offenbach

Hans Hauner, Prof

Role: STUDY_DIRECTOR

Technical University of Munic

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Heinrich-Heine-University, Rhineland State Clinics Düsseldorf

Düsseldorf, Rhineland State, Germany

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Germany

References

Explore related publications, articles, or registry entries linked to this study.

Hauner H, Rohrig K, Hebebrand J, Skurk T. No evidence for a direct effect of clozapine on fat-cell formation and production of leptin and other fat-cell-derived factors. Mol Psychiatry. 2003 Mar;8(3):258-9. doi: 10.1038/sj.mp.4001246. No abstract available.

Reference Type BACKGROUND
PMID: 12660797 (View on PubMed)

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

F1D-SB-018

Identifier Type: -

Identifier Source: org_study_id