Gastrectomy Study: Study to Investigate the Effect of Creon 25000 Minimicrospheres on Body Mass Index (BMI) in Patients After Gastrectomy

NCT ID: NCT00160186

Last Updated: 2008-03-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2003-12-31

Study Completion Date

2006-05-31

Brief Summary

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The purpose of this study is to investigate BMI and the nutritional parameters of Creon (pancreatin) versus placebo after a total or subtotal gastrectomy.

Detailed Description

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Conditions

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Gastrectomy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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1

Group Type EXPERIMENTAL

Pancreatin

Intervention Type DRUG

2 capsules Pancreatin with 25 000 lipase units per main meal (3 meals) and 1 capsule per snack (2-3 snacks)

2

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type DRUG

Placebo

Interventions

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Pancreatin

2 capsules Pancreatin with 25 000 lipase units per main meal (3 meals) and 1 capsule per snack (2-3 snacks)

Intervention Type DRUG

Placebo

Placebo

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Informed consent
* Males or females
* Age \>= 18 years
* Total or subtotal gastrectomy
* Females having negative pregnancy test or being surgically sterile or 1 year postmenopausal; women of childbearing age must use effective birth control.

Exclusion Criteria

* Diseases or conditions limiting the participation in, or completion of, the study
* Progressive tumors/metastasis
* Complications leading to insufficient peroral nutrition
* Known allergy to pancreatin
* Known exocrine insufficiency
* Experimental drug intake
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Solvay Pharmaceuticals

INDUSTRY

Sponsor Role lead

Responsible Party

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Solvay Pharmaceuticals

Principal Investigators

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Global Clinical Director Solvay

Role: STUDY_DIRECTOR

Solvay Pharmaceuticals

Locations

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Site 9

Odense, , Denmark

Site Status

Site 10

Tampere, , Finland

Site Status

Site 1

Bergen, , Norway

Site Status

Site 2

Fredrikstad, , Norway

Site Status

Site 3

Tromsø, , Norway

Site Status

Site 5

Linköping, , Sweden

Site Status

Site 7

Malmo, , Sweden

Site Status

Site 6

Stockholm, , Sweden

Site Status

Site 8

Stockholm, , Sweden

Site Status

Countries

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Denmark Finland Norway Sweden

Other Identifiers

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S245.4.007

Identifier Type: -

Identifier Source: org_study_id