The Relationship Between Voiding Dysfunction and Intravesical Sensory Threshold in Diabetes Women

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Total Enrollment

120 participants

Study Classification

OBSERVATIONAL

Study Completion Date

2006-12-31

Brief Summary

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The investigators will recruit a cross-sectional group of diabetic women in internist clinics. UDS will be applied for voiding function in each case. Intravesical electrical stimulation will be used to test CPT per 5 Hz, 250 Hz, 2000 Hz for the patients. The differences of intravesical CPT between diabetic women with and without voiding dysfunction will be determined.

Detailed Description

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Diabetes is a common metabolic disease of multiorgan involvement. The American Diabetes Association reported that the prevalence of diagnosed and undiagnosed diabetes mellitus (DM) in the United States is currently 6% and rising. The increase is secondary to a rising incident in obesity, as well as a change in the criteria for the diagnosis of DM from a fasting blood glucose 140 mg/dl to 126 mg/dl. Besides impaired blood glucose regulation, many direct and indirect sequelae of DM can occur. Triopathy of diabetes including retinopathy, neuropathy, and nephropathy are familiar to every internist. Lower urinary tract dysfunction is one of the most common complications in this group of patients.

We look at the difference of intravesical sensation in diabetic women by current perception test; then, we can find the patient with diabetic cystopathy in early stage. We compare the groups of diabetic women with or without voiding dysfunction by urodynamic study. CPT test for intravesical sensation will be applied.

Conditions

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Diabetes Mellitus

Keywords

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diabetic cystopathy bladder voiding dysfunction current perception test

Study Design

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Study Time Perspective

PROSPECTIVE

Interventions

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intravesical current perception test

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* The diabetic women followed up in specialist clinics over one year at National Taiwan University Hospital (NTUH)

Exclusion Criteria

* Concurrent neurological problems or other medical conditions that might interfere with voiding function
* Acute urinary tract infection (UTI)
* Previous pelvic surgery
* Vaginal prolapse

Minimum Eligible Age

30 Years

Maximum Eligible Age

85 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Principal Investigators

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Hong Jeng Yu, MD

Role: STUDY_CHAIR

Unaffliated

Other Identifiers

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31MD01

Identifier Type: -

Identifier Source: org_study_id