Multicentric, Prospective, Randomized, Comparing Trial Between Bypass of the Femoropoplitea by PTFE and Heparin Bounded PTFE

NCT ID: NCT00147979

Last Updated: 2014-12-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

596 participants

Study Classification

INTERVENTIONAL

Study Start Date

2004-04-30

Study Completion Date

2013-08-31

Brief Summary

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Comparison of two kinds of protheses for bridging of the femoropoplitea and/or femorotibiale: PTFE with or without bounded heparin

Detailed Description

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Comparison of two kinds of protheses for bridging of the femoropoplitea and/or femorotibiale: PTFE with or without bounded heparin.

Evaluation of this comparison by clinical systems: ankle-arm index, duplex echo, follow-up of 2 years

Conditions

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Peripheral Vascular Diseases

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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1

PTFE with bounded heparin

Group Type EXPERIMENTAL

Bridging by PTFE with bounded heparin

Intervention Type DEVICE

Bridging by PTFE with bounded heparin

2

PTFE without bounded heparin

Group Type ACTIVE_COMPARATOR

Bridging by PTFE without bounded heparin

Intervention Type DEVICE

Bridging by PTFE without bounded heparin

Interventions

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Bridging by PTFE with bounded heparin

Bridging by PTFE with bounded heparin

Intervention Type DEVICE

Bridging by PTFE without bounded heparin

Bridging by PTFE without bounded heparin

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Patients with Peripheral Vascular Diseases with complaints of invalidating claudication, rest pain, ucera or gangrene
* Patients with damage of the arteria femoralis superficialis or poplitea, longer than 6 cm
* Reasonable outflow arteria
* Informed consent
* Patient able to take part in all follow-up examinations

Exclusion Criteria

* Acute ischemia of the leg
* Patients with a ipsilateral inflow stenosis of more than 70% which can not be corrected before or during the surgery
* \< 18 years
* Pregnancy
* Recent heart attack (\< 1 month)
* Life expectancy less than 12 months
* Known allergy to heparin
* Known contrast allergy
* Known bleeding or coagulation disorder
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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JOTEC Company

OTHER

Sponsor Role collaborator

University Hospital, Ghent

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Frank Vermassen, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

University Hospital, Ghent

Locations

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University Hospital Ghent

Ghent, , Belgium

Site Status

Countries

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Belgium

Related Links

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http://www.uzgent.be

Website University Hospital Ghent

Other Identifiers

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2004/042

Identifier Type: -

Identifier Source: org_study_id