Amlodipine vs Nitrates Study in Patients With Chronic Stable Angina

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

200 participants

Study Classification

INTERVENTIONAL

Study Start Date

2001-04-30

Study Completion Date

2005-01-31

Brief Summary

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The objective of study is to compare the anti-ischemic efficacy and safety profiles of once daily amlodipine or isosorbide-5-mononitrate in the treatment of stable asymptomatic and symptomatic myocardial ischemia

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Detailed Description

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Conditions

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Myocardial Ischemia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Interventions

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Amlodipine

Intervention Type DRUG

iso- 5 - mononitrate

Intervention Type DRUG

Blood tests

Intervention Type PROCEDURE

Exercise Stress Test

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Outpatients \> =18 years of age with diagnosed clinically stable angina pectoris

Exclusion Criteria

* Patients with congestive heart failure, clinically significant cardiovascular disease, standing systolic blood pressure of less than 100mmHg, concomitant anti-anginal therapies similar to sublingual NTG

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No