The Efficacy of Re-treatment With Sulfadoxine-pyrimethamine in Children
NCT ID: NCT00137553
Last Updated: 2010-03-16
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE4
60 participants
INTERVENTIONAL
2001-05-31
2004-03-31
Brief Summary
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To compare the actual efficacy of SP with that in 1995 - 1996 we, the investigators of the Bandim Health Project, will visit these children once a week for 5 weeks. A finger prick blood sample will be collected for a malaria test.
Children with malaria during follow-up will be treated according to the guidelines of the Bandim Health Centre.
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Detailed Description
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In 1995 - 1996 the efficacy of this re-treatment regimen was evaluated in the same area.
To evaluate if treatment with SP is still efficient we want to follow children included in a study comparing treatment with chloroquine and amodiaquine having recrudescent malaria for 35 days following the re-treatment with SP.
Children with reappearing parasitaemia will be treated with SP. If accepting to participate in this study the children will be visited once a week and a capillary blood sample will be drawn. The blood sample taken on the day of reappearing parasitaemia in the chloroquine/amodiaquine study will be used as the day 0 blood sample in the SP-study.
If the child gets malaria during the follow-up he will be treated according to the guidelines of the Bandim Health Centre. All treatment during follow-up will be free.
Conditions
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Study Design
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NON_RANDOMIZED
SINGLE_GROUP
TREATMENT
NONE
Interventions
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Sulfadoxine-pyrimethamine (Fansidar)
Eligibility Criteria
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Inclusion Criteria
* \> 20 parasites per 200 leukocytes
* Treatment failure in a study comparing chloroquine and amodiaquine
* Informed consent
Exclusion Criteria
15 Years
ALL
No
Sponsors
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Bandim Health Project
OTHER
Principal Investigators
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Peter Aaby, Professor
Role: STUDY_DIRECTOR
Bandim Health Project
Locations
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Bandim Health Project
Apartado 861, Bissau Region, Guinea-Bissau
Countries
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Other Identifiers
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PSB-2001-Fansidar
Identifier Type: -
Identifier Source: org_study_id
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