Clinical Effect Of Cross Titration Of Antipsychotics With Ziprasidone In Schizophrenia Or Schizoaffective Disorder

NCT ID: NCT00137020

Last Updated: 2021-02-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

294 participants

Study Classification

INTERVENTIONAL

Study Start Date

2004-11-30

Study Completion Date

2006-04-30

Brief Summary

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The primary objective is to compare effectiveness of ziprasidone treatment to current treatments (haloperidol, olanzapine or risperidone) measured by change in Brief Psychiatric Rating Scale (BPRS) scores versus baseline

Detailed Description

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Conditions

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Schizophrenia Psychotic Disorders

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Interventions

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ziprasidone

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Primary diagnosis of schizophrenia or schizoaffective disorder, using DSM-IV criteria.
* Currently receiving either haloperidol, olanzapine or risperidone within -/+ 25% of the recommended daily dose (as delineated by the medication's package insert

Exclusion Criteria

* Resistance to conventional antipsychotic drugs
* With antipsychotic agents other than olanzapine, risperidone or haloperidol at start of treatment regimen within 12 hours prior to first dose of study drug
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Pfizer's Upjohn has merged with Mylan to form Viatris Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Pfizer CT.gov Call Center

Role: STUDY_DIRECTOR

Pfizer

Locations

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Pfizer Investigational Site

Alexandria, , Egypt

Site Status

Pfizer Investigational Site

Asyut, , Egypt

Site Status

Pfizer Investigational Site

Cairo, , Egypt

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Pfizer Investigational Site

Tanta, , Egypt

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Pfizer Investigational Site

Larissa, Mezourlo, Greece

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Pfizer Investigational Site

Athens, , Greece

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Pfizer Investigational Site

Athens, , Greece

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Pfizer Investigational Site

Athens, , Greece

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Pfizer Investigational Site

Jordan, , Jordan

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Pfizer Investigational Site

Kuwait City, , Kuwait

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Pfizer Investigational Site

Beirut, , Lebanon

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Pfizer Investigational Site

Khobar, , Saudi Arabia

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Pfizer Investigational Site

Garankuwa, Gauteng, South Africa

Site Status

Pfizer Investigational Site

Krugersdorp, Gauteng, South Africa

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Pfizer Investigational Site

Noordheuwel, Krugersdorp, Gauteng, South Africa

Site Status

Pfizer Investigational Site

Bellair, Durban, KwaZulu-Natal, South Africa

Site Status

Pfizer Investigational Site

Pinetown, Durban, KwaZulu-Natal, South Africa

Site Status

Pfizer Investigational Site

Observatory, Cape Town, Western Cape, South Africa

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Pfizer Investigational Site

Ankara, , Turkey (Türkiye)

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Pfizer Investigational Site

Bursa, , Turkey (Türkiye)

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Pfizer Investigational Site

Erzurum, , Turkey (Türkiye)

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Pfizer Investigational Site

Istanbul, , Turkey (Türkiye)

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Pfizer Investigational Site

Izmir, , Turkey (Türkiye)

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Pfizer Investigational Site

Izmir, , Turkey (Türkiye)

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Pfizer Investigational Site

Manisa, , Turkey (Türkiye)

Site Status

Pfizer Investigational Site

Şişli, , Turkey (Türkiye)

Site Status

Pfizer Investigational Site

Dubai, , United Arab Emirates

Site Status

Countries

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Egypt Greece Jordan Kuwait Lebanon Saudi Arabia South Africa Turkey (Türkiye) United Arab Emirates

Related Links

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Other Identifiers

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A1281117

Identifier Type: -

Identifier Source: org_study_id

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