ULTRA Study for Pacemaker Patients

NCT ID: NCT00133289

Last Updated: 2007-07-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

950 participants

Study Classification

INTERVENTIONAL

Study Start Date

2005-07-31

Study Completion Date

2007-06-30

Brief Summary

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The ULTRA study will assess the difference in average ventricular voltage output for pacemaker patients randomized to Automatic Capture feature ON versus patients randomized to Automatic Capture feature OFF.

Detailed Description

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Conditions

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Bradycardia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Interventions

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Pacemaker with Automatic Capture

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Patients who meet current INSIGNIA® Ultra pacemaker indications
* Patients who will be programmed to a pacing mode of DDD, DDDR, VVI, VVIR, or VDD at the time of implant
* Patients who sign and date a Patient Informed Consent form at or prior to the implant visit
* Patients who remain in the clinical care of the enrolling physician in approved centers

Exclusion Criteria

* Patients who will receive a single chamber device with an atrial lead only
* Patients who have chronic leads with a ventricular threshold of more than 4.0 V
* Patients whose life expectancy is less than 12 months
* Patients who are expected to receive a heart transplant during the duration of the study
* Patients who have or who are likely to receive a tricuspid valve prosthesis
* Patients who are currently enrolled in another investigational study that would directly impact the treatment or outcome of the ULTRA study.
* Patients who are younger than 18 years of age
* Patients who are pregnant
* Patients who are mentally incompetent and cannot sign a Patient Informed Consent form or comply with the study
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Boston Scientific Corporation

INDUSTRY

Sponsor Role lead

Principal Investigators

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Bruce Koplan, MD

Role: PRINCIPAL_INVESTIGATOR

Brigham and Women's Hospital

Locations

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Brigham and Women's Hospital

Boston, Massachusetts, United States

Site Status

Countries

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United States

References

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Choi HY, Noh YH, Jin SJ, Kim YH, Kim MJ, Sung H, Jang SB, Lee SJ, Bae KS, Lim HS. Bioavailability and tolerability of combination treatment with revaprazan 200 mg + itopride 150 mg: a randomized crossover study in healthy male Korean volunteers. Clin Ther. 2012 Sep;34(9):1999-2010. doi: 10.1016/j.clinthera.2012.07.004. Epub 2012 Aug 1.

Reference Type DERIVED
PMID: 22858177 (View on PubMed)

Other Identifiers

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CR-CA-051205-B

Identifier Type: -

Identifier Source: org_study_id