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Evaluation of Acetabular Perfusion After Ganz Osteotomy by Positron Emission Tomography

NCT ID: NCT00119444

Last Updated: 2015-11-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

12 participants

Study Classification

INTERVENTIONAL

Study Start Date

2004-01-31

Study Completion Date

2009-08-31

Brief Summary

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The purpose of this study is to examine the blood flow in acetabulum after periacetabular osteotomy by Positron Emission Tomography (PET).

Detailed Description

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As a consequence of periacetabular osteotomy the blood flow in acetabulum is decreased. After periacetabular osteotomy has been performed there is fine contact between the osteotomised acetabulum and the rest of the pelvis and the potential for healing is good. However, it has not been investigated how much the blood flow in acetabulum is changed after surgery. The blood flow is considered to be vital for how the pelvis heals after surgery. Most likely, the blood flow is important in relation to which degree osteoarthritis can be prevented after periacetabular osteotomy.

It is possible to estimate the blood flow by Positron Emission Tomography of the dysplastic hip joint pre- and postoperatively. In this study the blood flow and fluoride uptake is quantified by Positron emission tomography based on measurements of O-15 water and F-18 fluoride.

Conditions

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Osteoarthritis

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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periacetabular osteotomy

Group Type OTHER

Periacetabular osteotomy

Intervention Type PROCEDURE

osteotomy of the pelvis to increase acetabular coverage

Interventions

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Periacetabular osteotomy

osteotomy of the pelvis to increase acetabular coverage

Intervention Type PROCEDURE

Other Intervention Names

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PAO

Eligibility Criteria

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Inclusion Criteria

* Patients with radiologically diagnosed hip dysplasia (CE-angle \< 25°).
* Patients with osteoarthritis graded 0, 1 or 2 defined according to Tönnis' classification. Patients with pain from hip
* Age \> 18 years.
* Minimum 110° flexion in hip joint and closed growth zones in the pelvic.
* Informed consent.

Exclusion Criteria

* Patients with neurological diseases
* Patients with calvé-Legg-Perthes syndrome.
* Patients where an femoral intertrochanteric osteotomy is necessary.
* Patients with medical sequelae after earlier hip surgery.
* Females who are pregnant.
* Patients with metal implants.
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Aarhus

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Kjeld Søballe, MD, Prof.

Role: PRINCIPAL_INVESTIGATOR

Orthopaedic Center, Aarhus University Hospital, Aarhus, Denmark

Locations

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Orthopaedic Center, Aarhus University Hospital

Aarhus, , Denmark

Site Status

Countries

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Denmark

Other Identifiers

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20050606

Identifier Type: -

Identifier Source: org_study_id