Trial to Reduce Antimicrobial Prophylaxis Errors (TRAPE)
NCT ID: NCT00114036
Last Updated: 2005-06-24
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
INTERVENTIONAL
2002-08-31
2005-12-31
Brief Summary
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Detailed Description
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Our specific aims over the 4 year project period are:
1. determine the incidence of medication errors related to antimicrobial prophylaxis for cardiovascular surgery, joint replacement surgery, and hysterectomies in 44 hospitals recruited to participate in the study;
2. identify organizational and system factors associated with error rates;
3. randomize the 44 hospitals to evaluate the effectiveness of a multifaceted intervention.
The interventions consist of: a) the promotion of specific process changes likely to reduce error rates, b) a site-visit, c) customized process feedback, d) facilitated benchmarking, and e) peer consultation. The 22 intervention hospitals will be compared to 22 hospitals that receive written feedback of their error rates only. The study has 80% power to detect a 12-15% improvement in the timing of prophylaxis in the full intervention group compared to the written feedback only group. Data collection will be done at each participating hospital, and the medical records of 100 surgical patients before and after the intervention will be abstracted at each hospital to establish performance rates. Changes in the processes of care, and the evolution through stages of organizational change will also be assessed.
Conditions
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Keywords
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Study Design
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RANDOMIZED
PARALLEL
ECT
NONE
Interventions
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Quality improvement strategies
Eligibility Criteria
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Inclusion Criteria
No
Sponsors
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Joint Commission on Accreditation of Healthcare Organizations
OTHER
Society for Healthcare Epidemiology of America
OTHER
Centers for Disease Control and Prevention
FED
Agency for Healthcare Research and Quality (AHRQ)
FED
Principal Investigators
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Stephen B. Krichevsky, PhD
Role: PRINCIPAL_INVESTIGATOR
Wake Forest University Health Sciences
Barbara I. Braun, PhD
Role: STUDY_DIRECTOR
Joint Commission on Accreditation of Healthcare Organizations
Edward Wong, MD
Role: STUDY_CHAIR
VA Office of Research and Development
Steve Solomon, MD
Role: STUDY_CHAIR
Centers for Disease Control and Prevention
Bryan Simmons, MD
Role: STUDY_CHAIR
Methodist Health System
Andrew J. Bush, PhD
Role: STUDY_CHAIR
University of Tennessee
John Burke, MD
Role: STUDY_CHAIR
LDS Hospital
Michele R. Bozikis, MPH
Role: STUDY_CHAIR
Joint Commission on Accreditation of Healthcare Organizations
Linda Kusek, MPH
Role: STUDY_CHAIR
Joint Commission on Accreditation of Healthcare Organizations
Locations
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Joint Commission on Accreditation of Healthcare Organizations
Oakbrook Terrace, Illinois, United States
Wake Forest University School of Medicine
Winston-Salem, North Carolina, United States
University of Tennessee
Memphis, Tennessee, United States
Countries
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References
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Kritchevsky SB, Braun BI, Bush AJ, Bozikis MR, Kusek L, Burke JP, Wong ES, Jernigan J, Davis CC, Simmons B; TRAPE Study Group. The effect of a quality improvement collaborative to improve antimicrobial prophylaxis in surgical patients: a randomized trial. Ann Intern Med. 2008 Oct 7;149(7):472-80, W89-93. doi: 10.7326/0003-4819-149-7-200810070-00007.
Other Identifiers
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