Comparison of Continuing Olanzapine to Switching to Quetiapine in Overweight or Obese Patients With Schizophrenia and Schizoaffective Disorder

NCT ID: NCT00090012

Last Updated: 2007-11-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

340 participants

Study Classification

INTERVENTIONAL

Study Start Date

2004-07-31

Study Completion Date

2006-03-31

Brief Summary

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The purposes of this study are to determine:

* The effectiveness of olanzapine as compared to quetiapine in treating and preventing the recurrence of a variety of symptoms of schizophrenia and schizoaffective disorder in patients who are obese or overweight.
* The safety of olanzapine as compared to quetiapine.

Detailed Description

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Conditions

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Schizophrenia Schizoaffective Disorder

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Interventions

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Olanzapine

Intervention Type DRUG

Quetiapine

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* You must be 18-75 years of age and be diagnosed with schizophrenia or schizoaffective disorder
* You must be able to visit the doctor's office thirteen (13) times over a twenty-six (26) week period

Exclusion Criteria

* You are a woman and are pregnant or breastfeeding
* You have an acute or unstable medical illness, such as heart, liver, or kidney disease, or you have a seizure disorder. (Note: If you are uncertain about a particular condition, please discuss it with your physician.)
* You have a history of allergic reaction or intolerance to olanzapine or quetiapine
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Eli Lilly and Company

INDUSTRY

Sponsor Role lead

Principal Investigators

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Call1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon-Fri 9 AM - 5 PM Eastern time (UTC/GMT - 5 hours, EST)

Role: STUDY_DIRECTOR

Eli Lilly and Company

Locations

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For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559 or 317-615-4559) Mon-Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

Garden Grove, California, United States

Site Status

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La Mesa, California, United States

Site Status

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San Diego, California, United States

Site Status

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Washington D.C., District of Columbia, United States

Site Status

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Miami, Florida, United States

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Granite City, Illinois, United States

Site Status

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Lafayette, Indiana, United States

Site Status

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Lake Charles, Louisiana, United States

Site Status

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Baltimore, Maryland, United States

Site Status

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Detroit, Michigan, United States

Site Status

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Omaha, Nebraska, United States

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Nashua, New Hampshire, United States

Site Status

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Clementon, New Jersey, United States

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Kenilworth, New Jersey, United States

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Neptune City, New Jersey, United States

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Princeton, New Jersey, United States

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Brooklyn, New York, United States

Site Status

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New York, New York, United States

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Olean, New York, United States

Site Status

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Rochester, New York, United States

Site Status

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Cleveland, Ohio, United States

Site Status

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Springfield, Oregon, United States

Site Status

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Paoli, Pennsylvania, United States

Site Status

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Conroe, Texas, United States

Site Status

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Waco, Texas, United States

Site Status

Countries

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Puerto Rico United States

Other Identifiers

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F1D-US-HGLR

Identifier Type: -

Identifier Source: secondary_id

8894

Identifier Type: -

Identifier Source: org_study_id