Suboxone: (Buprenorphine/Naloxone) Comparison of Two Taper Schedules - 1

NCT ID: NCT00078117

Last Updated: 2017-01-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

516 participants

Study Classification

INTERVENTIONAL

Study Start Date

2003-06-30

Study Completion Date

2005-05-31

Brief Summary

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The purpose of this protocol is to to compare the clinical utility of two dosage tapering regimens in Buprenorphine/Naloxone stabilized subjects for opiate detoxification.

Detailed Description

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Conditions

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Opioid-Related Disorders

Study Design

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Primary Study Purpose

TREATMENT

Interventions

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Buprenorphine

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Females are not pregnant or lactating
* Subjects meet DSM-IV criteria for opiate dependence, are medically and psychiatrically stable, and do not have a current history of benzodiazepine dependence abuse, dependence, or treatment
Minimum Eligible Age

15 Years

Maximum Eligible Age

99 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of California, Los Angeles

OTHER

Sponsor Role lead

Responsible Party

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University of California, Los Angeles

Principal Investigators

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Walter Ling, M.D.

Role: PRINCIPAL_INVESTIGATOR

University of California, Los Angeles

Locations

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Addiction Research & Treatment Services (ARTS)

Denver, Colorado, United States

Site Status

Denver Health & Hospitals Authority

Denver, Colorado, United States

Site Status

Hartford Dispensary

Hartford, Connecticut, United States

Site Status

Connecticut Counseling Centers

Waterbury, Connecticut, United States

Site Status

LI Jewish Health System

Glen Oaks, New York, United States

Site Status

New York VA Medical Center

New York, New York, United States

Site Status

South Light-Wakeview Clinic

Raleigh, North Carolina, United States

Site Status

Coastal Horizons Center, Inc.

Wilmington, North Carolina, United States

Site Status

CODA

Portland, Oregon, United States

Site Status

Norfolk CSB

Norfolk, Virginia, United States

Site Status

Providence Behavioral Health Services

Everett, Washington, United States

Site Status

Countries

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United States

References

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Nielsen S, Hillhouse M, Thomas C, Hasson A, Ling W. A comparison of buprenorphine taper outcomes between prescription opioid and heroin users. J Addict Med. 2013 Jan-Feb;7(1):33-8. doi: 10.1097/ADM.0b013e318277e92e.

Reference Type DERIVED
PMID: 23222095 (View on PubMed)

Hillhouse M, Canamar CP, Ling W. Predictors of outcome after short-term stabilization with buprenorphine. J Subst Abuse Treat. 2013 Mar;44(3):336-42. doi: 10.1016/j.jsat.2012.08.016. Epub 2012 Sep 26.

Reference Type DERIVED
PMID: 23021099 (View on PubMed)

Back SE, Payne RL, Wahlquist AH, Carter RE, Stroud Z, Haynes L, Hillhouse M, Brady KT, Ling W. Comparative profiles of men and women with opioid dependence: results from a national multisite effectiveness trial. Am J Drug Alcohol Abuse. 2011 Sep;37(5):313-23. doi: 10.3109/00952990.2011.596982.

Reference Type DERIVED
PMID: 21854273 (View on PubMed)

Ling W, Hillhouse M, Domier C, Doraimani G, Hunter J, Thomas C, Jenkins J, Hasson A, Annon J, Saxon A, Selzer J, Boverman J, Bilangi R. Buprenorphine tapering schedule and illicit opioid use. Addiction. 2009 Feb;104(2):256-65. doi: 10.1111/j.1360-0443.2008.02455.x.

Reference Type DERIVED
PMID: 19149822 (View on PubMed)

Other Identifiers

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NIDA-CTN-0003-1

Identifier Type: -

Identifier Source: org_study_id

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