A Study of ABT-751 in Patients With Non-Small Cell Lung Cancer

NCT ID: NCT00073151

Last Updated: 2007-11-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE2

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2003-09-30

Study Completion Date

2006-01-31

Brief Summary

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The purpose of the study is to determine if ABT-751 will decrease tumors, and determine how long the tumor shrinkage can be maintained in patients with non-small cell lung cancer. Patients will receive ABT-751 by mouth daily for 21 days. Patients will be off drug for 7 days before starting the next cycle of drug.

Detailed Description

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Conditions

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Non-Small Cell Lung Cancer

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Interventions

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ABT-751

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Stage IIIB or IV non-small cell lung cancer.
* Recurrent tumor following treatment with paclitaxel or docetaxel.
* Able to tolerate normal activities of daily living.
* Adequate bone marrow, kidney and liver function.

Exclusion Criteria

* Pregnant or breast feeding.
* Anti-tumor therapy within 4 weeks of the start of ABT-751 administration.
* CNS metastasis.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Abbott

INDUSTRY

Sponsor Role lead

Principal Investigators

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Helen Eliopoulos, MD

Role: STUDY_DIRECTOR

Abbott

Locations

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Oncology Hematology Group of South Florida

Miami, Florida, United States

Site Status

Florida Cancer Institute

New Port Richey, Florida, United States

Site Status

University of Chicago Medical Center

Chicago, Illinois, United States

Site Status

University of Maryland Greenbaum Cancer Center

Baltimore, Maryland, United States

Site Status

Oncology & Hematology Associates of Kansas City, PA

Kansas City, Missouri, United States

Site Status

Washington University School of Medicine

St Louis, Missouri, United States

Site Status

Albany Regional Cancer Center

Albany, New York, United States

Site Status

Raleigh Hematology Oncology

Cary, North Carolina, United States

Site Status

Dayton Oncology and Hematology

Kettering, Ohio, United States

Site Status

Cancer Care Associates

Oklahoma City, Oklahoma, United States

Site Status

Cancer Centers of the Carolinas

Greenville, South Carolina, United States

Site Status

West Cancer Clinic

Memphis, Tennessee, United States

Site Status

Texas Oncology

Dallas, Texas, United States

Site Status

Texas Oncology

Fort Worth, Texas, United States

Site Status

Cancer Care Northwest

Spokane, Washington, United States

Site Status

Northwest Cancer Specialists

Vancouver, Washington, United States

Site Status

University of Wisconsin Comprehensive Cancer Center

Madison, Wisconsin, United States

Site Status

Countries

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United States

Other Identifiers

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M02-448

Identifier Type: -

Identifier Source: org_study_id

NCT00080730

Identifier Type: -

Identifier Source: nct_alias