A Study of ABT-751 in Patients With Renal Cell Cancer

NCT ID: NCT00073112

Last Updated: 2007-11-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE2

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2003-08-31

Study Completion Date

2006-09-30

Brief Summary

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The purpose of the study is to determine if ABT-751 will decrease tumors, and determine how long the tumor shrinkage can be maintained in patients with renal cell cancer. Patients will receive ABT-751 by mouth daily for 21 days. Patients will be off drug for 7 days before starting the next cycle of drug.

Detailed Description

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Conditions

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Renal Cell Cancer

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Interventions

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ABT-751

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Renal Cell Carcinoma.
* Recurrent tumor.
* At least 6 weeks post-nephrectomy.
* Able to tolerate normal activities of daily living.
* Adequate bone marrow, kidney, and liver function.

Exclusion Criteria

* Pregnant or breast feeding.
* Anti-tumor therapy within 4 weeks of the start of ABT-751 administration.
* CNS metastasis.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Abbott

INDUSTRY

Sponsor Role lead

Principal Investigators

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Helen Eliopoulos, M.D.

Role: STUDY_DIRECTOR

Abbott

Locations

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Arizona Cancer Research Center

Tucson, Arizona, United States

Site Status

UCLA School of Medicine

Los Angeles, California, United States

Site Status

Clinical Trials + Research Associates

Montebello, California, United States

Site Status

US Oncology Inc Rocky Mountain Cancer Centers

Denver, Colorado, United States

Site Status

Oncology Hematology Group of South Florida

Miami, Florida, United States

Site Status

US Oncology Inc Florida Cancer Institute

New Port Richey, Florida, United States

Site Status

US Oncology Inc Ocala Oncology Center

Ocala, Florida, United States

Site Status

US Oncology Inc Cancer Centers of Florida, P.A.

Orlando, Florida, United States

Site Status

University of Chicago Medical Center

Chicago, Illinois, United States

Site Status

Sidney Kimmel Comprehensive Cancer Center

Baltimore, Maryland, United States

Site Status

US Oncology Inc Raleigh Hematology Oncology Clinic

Cary, North Carolina, United States

Site Status

US Oncology Inc Dayton Oncology & Hematology P.A.

Kettering, Ohio, United States

Site Status

US Oncology Inc Cancer Care Accociates-Mercy Campus

Oklahoma City, Oklahoma, United States

Site Status

US Oncology Inc Cancer Centers of the Carolinas

Greenville, South Carolina, United States

Site Status

West Cancer Clinic

Memphis, Tennessee, United States

Site Status

Vanderbilt Ingram Cancer Center

Nashville, Tennessee, United States

Site Status

US Oncology Inc Tyler Cancer Center

Tyler, Texas, United States

Site Status

US Oncology Inc Cancer Care Northwest-North

Spokane, Washington, United States

Site Status

US Oncology Inc Northwest Cancer Specialists

Vancouver, Washington, United States

Site Status

B.C. Vancouver Cancer Agency

Vancouver, British Columbia, Canada

Site Status

Queen Elizabeth II Health Science Centre

Halifax, Nova Scotia, Canada

Site Status

McMaster University

Hamilton, Ontario, Canada

Site Status

McGill University

Montreal, Quebec, Canada

Site Status

Countries

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United States Canada

Other Identifiers

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M02-416

Identifier Type: -

Identifier Source: org_study_id

NCT00080717

Identifier Type: -

Identifier Source: nct_alias