Study of Decision Making in Patients Participating in Phase I Clinical Trials

NCT ID: NCT00054223

Last Updated: 2012-03-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

250 participants

Study Classification

INTERVENTIONAL

Study Start Date

2003-01-31

Study Completion Date

2005-11-30

Brief Summary

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RATIONALE: Studying individuals who are enrolled in phase I clinical trials may help to improve the way in which clinical trials are conducted.

PURPOSE: This clinical trial is studying patients' personality traits, reasons for participating in the trial, and understanding of their medical situation, prognosis, and risks and benefits of participating in a phase I trial.

Detailed Description

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OBJECTIVES:

* Determine the range of personality traits of patients enrolled in a phase I clinical trial.
* Determine these patients' understanding of their medical situation and prognosis.
* Determine these patients' understanding of risks and benefits of phase I clinical trials.
* Determine these patients' reasons for participating in a phase I clinical trial.
* Determine the risk/benefit trade-offs of these patients.
* Determine the existential outlook of these patients.
* Determine the information gathering nature of these patients.

OUTLINE: This is a multicenter study.

Before beginning phase I clinical trial treatment, patients complete a survey over 30-45 minutes administered by an interviewer. Patients then self-administer the Temperament and Character Inventory assessment over 30 minutes.

PROJECTED ACCRUAL: Approximately 250 patients will be accrued for this study within 6 months.

Conditions

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Psychosocial Effects of Cancer and Its Treatment Unspecified Adult Solid Tumor, Protocol Specific

Study Design

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Blinding Strategy

NONE

Interventions

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psychosocial assessment and care

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

DISEASE CHARACTERISTICS:

* Consented to enrollment in a phase I cancer clinical trial

PATIENT CHARACTERISTICS:

Age

* 18 and over

Performance status

* Not specified

Life expectancy

* Not specified

Hematopoietic

* Not specified

Hepatic

* Not specified

Renal

* Not specified

Other

* Understands written English

PRIOR CONCURRENT THERAPY:

Biologic therapy

* Not specified

Chemotherapy

* Not specified

Endocrine therapy

* Not specified

Radiotherapy

* Not specified

Surgery

* Not specified

Other

* No concurrent enrollment in other clinical trials evaluating phase I patient attitudes
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Cancer Institute (NCI)

NIH

Sponsor Role collaborator

National Institutes of Health Clinical Center (CC)

NIH

Sponsor Role lead

Principal Investigators

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Manish Agrawal, MD

Role: STUDY_CHAIR

National Cancer Institute (NCI)

Locations

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Robert H. Lurie Comprehensive Cancer Center at Northwestern University

Chicago, Illinois, United States

Site Status

Warren Grant Magnuson Clinical Center - NCI Clinical Trials Referral Office

Bethesda, Maryland, United States

Site Status

Fox Chase Cancer Center - Philadelphia

Philadelphia, Pennsylvania, United States

Site Status

M. D. Anderson Cancer Center at University of Texas

Houston, Texas, United States

Site Status

Cancer Therapy and Research Center

San Antonio, Texas, United States

Site Status

Countries

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United States

Other Identifiers

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03-CC-0063

Identifier Type: -

Identifier Source: secondary_id

CDR0000269911

Identifier Type: -

Identifier Source: secondary_id

030063

Identifier Type: -

Identifier Source: org_study_id

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