EVA: Evista Alendronate Comparison

NCT ID: NCT00035971

Last Updated: 2006-07-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Study Classification

INTERVENTIONAL

Brief Summary

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The purpose of this study is to determine how treatment with raloxifene compares to treatment with alendronate in postmenopausal women with osteoporosis on the chance of experiencing fractures

Detailed Description

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Conditions

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Osteoporosis

Study Design

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Primary Study Purpose

TREATMENT

Interventions

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raloxifene HCI and alendronate Na

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* 50-80 years of age, inclusive
* 2 years since last menses
* Dx femoral neck osteoporosis
* No vertebral fractures

Exclusion Criteria

* Poor candidate for study drugs
* Hx of diseases affecting bone metabolism
* Hx of breast/estrogen-dependent cancer
* Current use of osteoporosis drug therapy
* Hx/high risk of VTE
Minimum Eligible Age

50 Years

Maximum Eligible Age

80 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Eli Lilly and Company

INDUSTRY

Sponsor Role lead

Locations

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Anniston, Alabama, United States

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Phoenix, Arizona, United States

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Scottsdale, Arizona, United States

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Tucson, Arizona, United States

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Anaheim, California, United States

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Beverly Hills, California, United States

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Loma Linda, California, United States

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Oakland, California, United States

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San Francisco, California, United States

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Walnut Creek, California, United States

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Lakewood, Colorado, United States

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Trumbull, Connecticut, United States

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Maitland, Florida, United States

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Miami, Florida, United States

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Tampa, Florida, United States

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West Palm Beach, Florida, United States

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Decatur, Georgia, United States

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Fayetteville, Georgia, United States

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Gainesville, Georgia, United States

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Riverdale, Georgia, United States

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Honolulu, Hawaii, United States

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Boise, Idaho, United States

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Idaho Falls, Idaho, United States

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Chicago, Illinois, United States

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Morton Grove, Illinois, United States

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Peoria, Illinois, United States

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Evansville, Indiana, United States

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Indianapolis, Indiana, United States

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Des Moines, Iowa, United States

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Overland Park, Kansas, United States

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Lexington, Kentucky, United States

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Bangor, Maine, United States

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Frederick, Maryland, United States

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Hagerstown, Maryland, United States

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Boston, Massachusetts, United States

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Detroit, Michigan, United States

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Minneapolis, Minnesota, United States

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Springfield, Missouri, United States

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St Louis, Missouri, United States

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Omaha, Nebraska, United States

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Lebanon, New Hampshire, United States

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Passaic, New Jersey, United States

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Albuquerque, New Mexico, United States

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Albany, New York, United States

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New York, New York, United States

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Rochester, New York, United States

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The Bronx, New York, United States

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Charlotte, North Carolina, United States

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Greensboro, North Carolina, United States

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Greenville, North Carolina, United States

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Morehead City, North Carolina, United States

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Beachwood, Ohio, United States

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Canton, Ohio, United States

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Cincinnati, Ohio, United States

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Tulsa, Oklahoma, United States

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Portland, Oregon, United States

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Philadelphia, Pennsylvania, United States

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Pittsburgh, Pennsylvania, United States

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Johnston, Rhode Island, United States

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Providence, Rhode Island, United States

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Austin, Texas, United States

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Dallas, Texas, United States

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San Antonio, Texas, United States

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Temple, Texas, United States

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Salt Lake City, Utah, United States

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Burlington, Vermont, United States

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Charlottesville, Virginia, United States

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Newport News, Virginia, United States

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Richmond, Virginia, United States

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Seattle, Washington, United States

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Spokane, Washington, United States

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Tacoma, Washington, United States

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Madison, Wisconsin, United States

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Calgary, Alberta, Canada

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Vancouver, British Columbia, Canada

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Winnipeg, Manitoba, Canada

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Moncton, New Brunswick, Canada

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Burlington, Ontario, Canada

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Greater Sudbury, Ontario, Canada

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Hamilton, Ontario, Canada

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Kitchener, Ontario, Canada

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Ottawa, Ontario, Canada

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Montreal, Quebec, Canada

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Sainte-Foy, Quebec, Canada

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Trois-Rivières, Quebec, Canada

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Saskatoon, Saskatchewan, Canada

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Countries

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United States Canada

References

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Recker RR, Kendler D, Recknor CP, Rooney TW, Lewiecki EM, Utian WH, Cauley JA, Lorraine J, Qu Y, Kulkarni PM, Gaich CL, Wong M, Plouffe L Jr, Stock JL. Comparative effects of raloxifene and alendronate on fracture outcomes in postmenopausal women with low bone mass. Bone. 2007 Apr;40(4):843-51. doi: 10.1016/j.bone.2006.11.001. Epub 2006 Dec 19.

Reference Type DERIVED
PMID: 17182297 (View on PubMed)

Other Identifiers

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H3S-US-GGKO

Identifier Type: -

Identifier Source: secondary_id

5548

Identifier Type: -

Identifier Source: org_study_id