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Treatment of Patients With Major Depressive Disorder With MK0869 (0869-063)

NCT ID: NCT00034944

Last Updated: 2017-05-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

495 participants

Study Classification

INTERVENTIONAL

Study Start Date

2002-01-24

Study Completion Date

2003-12-17

Brief Summary

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A clinical study to determine the efficacy and safety of MK0869 in the treatment of depression.

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Detailed Description

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The duration of treatment is 8 weeks.

Conditions

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Major Depressive Disorder

Study Design

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Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Interventions

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MK0869, aprepitant

Intervention Type DRUG

Comparator: placebo

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

Major depressive disorder
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Merck Sharp & Dohme LLC

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

References

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Keller M, Montgomery S, Ball W, Morrison M, Snavely D, Liu G, Hargreaves R, Hietala J, Lines C, Beebe K, Reines S. Lack of efficacy of the substance p (neurokinin1 receptor) antagonist aprepitant in the treatment of major depressive disorder. Biol Psychiatry. 2006 Feb 1;59(3):216-23. doi: 10.1016/j.biopsych.2005.07.013. Epub 2005 Oct 24.

Reference Type RESULT
PMID: 16248986 (View on PubMed)

Study Documents

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Document Type: CSR Synopsis

View Document

Other Identifiers

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2006_403

Identifier Type: -

Identifier Source: secondary_id

0869-063

Identifier Type: -

Identifier Source: org_study_id

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