Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE3
INTERVENTIONAL
2000-08-31
2003-10-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NON_RANDOMIZED
SINGLE_GROUP
TREATMENT
NONE
Interventions
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ZD1839 (Gefitinib)
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* previous documented histologically or cytologically confirmed non-small cell lung cancer;
* locally advanced and/or metastatic non-operable non-small cell lung cancer (stage III or IV)patients who have received at least one course of standard systemic chemotherapy or radiation therapy or are ineligible for chemotherapy or radiotherapy or are ineligible or not a candidate for enrollment on another ZD1839 trial or who, in the Investigator's opinion, are not medically suitable for chemotherapy.
* age 18 years or older;
* written informed consent to participate in the trial.
Exclusion Criteria
* receiving concurrent radiotherapy, chemotherapy, or other systemic anti-cancer medication or any other investigational agent. \* Non-cytotoxic or hormonal therapies for the adjuvant treatment of cancer or for previously treated cancers may be allowed per AstraZeneca permission;
* patients eligible for or previously enrolled on a ZD1839 blinded clinical trial protocol. Patients eligible for or previously enrolled on an open-label or unblinded ZD1839 clinical trial may be considered for acceptance into the Expanded Access Program with AstraZeneca permission;
* having other active malignancies;
* incomplete healing from previous oncologic or other major surgery;
* evidence of any other significant clinical disorder or laboratory finding that makes it undesirable for the patient to participate in the trial;
* pregnancy or breast feeding (women of child-bearing potential).
18 Years
ALL
No
Sponsors
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AstraZeneca
INDUSTRY
Principal Investigators
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Iressa Medical Science Director, MD
Role: STUDY_DIRECTOR
AstraZeneca
Locations
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Research Site
Alabaster, Alabama, United States
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Anniston, Alabama, United States
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Birmingham, Alabama, United States
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Gadsen, Alabama, United States
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Huntsville, Alabama, United States
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Montgomery, Alabama, United States
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Anchorage, Alaska, United States
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Fairbanks, Alaska, United States
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Mesa, Arizona, United States
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Phoenix, Arizona, United States
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Scottsdale, Arizona, United States
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Sedona, Arizona, United States
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Tucson, Arizona, United States
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Yuma, Arizona, United States
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Bentonville, Arkansas, United States
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Camden, Arkansas, United States
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Fort Smith, Arkansas, United States
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Little Rock, Arkansas, United States
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Anaheim, California, United States
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Arcadia, California, United States
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Bakersfield, California, United States
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Baldwin Park, California, United States
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Bellflower, California, United States
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Berkeley, California, United States
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Burbank, California, United States
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Campbell, California, United States
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Chico, California, United States
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Chino, California, United States
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Chule Vista, California, United States
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Concord, California, United States
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Duarte, California, United States
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Eureka, California, United States
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Fairfield, California, United States
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Fontana, California, United States
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Fountain Valley, California, United States
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Fresno, California, United States
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Fullerton, California, United States
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Gilroy, California, United States
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Grass Valley, California, United States
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Greenbrae, California, United States
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La Jolla, California, United States
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Lakewood, California, United States
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LaVerne, California, United States
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Loma Linda, California, United States
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Long Beach, California, United States
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Los Alamitos, California, United States
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Los Angeles, California, United States
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Los Gatos, California, United States
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Marina Del Ray, California, United States
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Mission Viejo, California, United States
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Montebello, California, United States
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Monterey, California, United States
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Newport Beach, California, United States
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Oakland, California, United States
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Oceanside, California, United States
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Orange, California, United States
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Oxnard, California, United States
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Palm Springs, California, United States
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Palo Alto, California, United States
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Panorama City, California, United States
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Petaluma, California, United States
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Pleasanton, California, United States
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Rancho Mirage, California, United States
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Redding, California, United States
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Redondo Beach, California, United States
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Redwood City, California, United States
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Riverside, California, United States
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Royal Grande, California, United States
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Sacramento, California, United States
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Salinas, California, United States
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San Diego, California, United States
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San Francisco, California, United States
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San Jose, California, United States
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San Luis Obispo, California, United States
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San Mateo, California, United States
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Santa Barbara, California, United States
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Santa Clara, California, United States
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Santa Cruz, California, United States
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Santa Maria, California, United States
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Santa Monica, California, United States
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Simi Valley, California, United States
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Soquel, California, United States
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Stockton, California, United States
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Sunnyvale, California, United States
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Sylmar, California, United States
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Tarzana, California, United States
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Thousand Oaks, California, United States
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Twentynine Palm, California, United States
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Upland, California, United States
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Vallejo, California, United States
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Van Nuys, California, United States
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Walnut Creek, California, United States
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Westlake Village, California, United States
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Woodland Hills, California, United States
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Boulder, Colorado, United States
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Denver, Colorado, United States
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Fort Collins, Colorado, United States
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Longmont, Colorado, United States
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Pueblo, Colorado, United States
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Danbury, Connecticut, United States
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Fairfield, Connecticut, United States
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Greenwich, Connecticut, United States
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Handen, Connecticut, United States
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Hartford, Connecticut, United States
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Manchester, Connecticut, United States
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Middletown, Connecticut, United States
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Milford, Connecticut, United States
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New London, Connecticut, United States
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New Milford, Connecticut, United States
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Norwalk, Connecticut, United States
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Norwich, Connecticut, United States
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Stamford, Connecticut, United States
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Torrington, Connecticut, United States
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Trumbull, Connecticut, United States
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Waterbury, Connecticut, United States
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Lewes, Delaware, United States
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Newark, Delaware, United States
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Washington D.C., District of Columbia, United States
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Boca Raton, Florida, United States
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Boynton Beach, Florida, United States
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Bradenton, Florida, United States
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Clearwater, Florida, United States
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Daytona Beach, Florida, United States
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Fort Myers, Florida, United States
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Gainesville, Florida, United States
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Jacksonville, Florida, United States
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Jupiter, Florida, United States
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Key West, Florida, United States
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Lake Worth, Florida, United States
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Lakeland, Florida, United States
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Leesburg, Florida, United States
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Melbourne, Florida, United States
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Miami, Florida, United States
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Miami Shores, Florida, United States
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Naples, Florida, United States
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New Port Richey, Florida, United States
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Ocala, Florida, United States
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Ocoee, Florida, United States
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Orange Park, Florida, United States
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Orlando, Florida, United States
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Ormand Beach, Florida, United States
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Palm Harbor, Florida, United States
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Panama City, Florida, United States
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Pensacola, Florida, United States
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Plantation, Florida, United States
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Port Charlotte, Florida, United States
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Port Saint Lucie, Florida, United States
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Saint Augustine, Florida, United States
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Sanford, Florida, United States
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Sarasota, Florida, United States
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St. Petersburg, Florida, United States
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Stuart, Florida, United States
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Tampa, Florida, United States
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Tavares, Florida, United States
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Vero Beach, Florida, United States
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West Palm Beach, Florida, United States
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Albany, Georgia, United States
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Athens, Georgia, United States
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Atlanta, Georgia, United States
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Brunswick, Georgia, United States
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Canton, Georgia, United States
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Carrollton, Georgia, United States
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Fort Gordon, Georgia, United States
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Macon, Georgia, United States
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Marietta, Georgia, United States
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Roswell, Georgia, United States
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Savannah, Georgia, United States
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Thomasville, Georgia, United States
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Tucker, Georgia, United States
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Valdosta, Georgia, United States
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Waycross, Georgia, United States
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Honolulu, Hawaii, United States
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Tripler AMC, Hawaii, United States
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Wailuku, Hawaii, United States
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Boise, Idaho, United States
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Coeur d'Alene, Idaho, United States
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Idaho Falls, Idaho, United States
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Arlington Heights, Illinois, United States
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Aurora, Illinois, United States
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Belleville, Illinois, United States
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Berwyn, Illinois, United States
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Champaign, Illinois, United States
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Chicago, Illinois, United States
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Chicago Heights, Illinois, United States
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Danville, Illinois, United States
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Decatur, Illinois, United States
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Des Plaines, Illinois, United States
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Elk Grove Village, Illinois, United States
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Elmhurst, Illinois, United States
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Evanston, Illinois, United States
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Flossmore, Illinois, United States
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Galesburg, Illinois, United States
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Geneva, Illinois, United States
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Harvey, Illinois, United States
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Hinsdale, IL, Illinois, United States
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Joliet, Illinois, United States
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La Grange, Illinois, United States
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Libertyville, Illinois, United States
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Maywood, Illinois, United States
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Moline, Illinois, United States
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Naperville, Illinois, United States
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Oak Lawn, Illinois, United States
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Park Ridge, Illinois, United States
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Peoria, Illinois, United States
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River Forest, Illinois, United States
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Rockford, Illinois, United States
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Skokie, Illinois, United States
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Springfield, Illinois, United States
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Urbana, Illinois, United States
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Wheaton, Illinois, United States
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Zion, Illinois, United States
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Bloomington, Indiana, United States
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Evansville, Indiana, United States
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Fort Wayne, Indiana, United States
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Indianapolis, Indiana, United States
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Jasper, Indiana, United States
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Merrillville, Indiana, United States
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Michigan City, Indiana, United States
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Muncie, Indiana, United States
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Munster, Indiana, United States
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New Albany, Indiana, United States
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South Bend, Indiana, United States
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Terre Haute, Indiana, United States
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Ames, Iowa, United States
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Bettendorf, Iowa, United States
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Davenport, Iowa, United States
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Des Moines, Iowa, United States
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Iowa City, Iowa, United States
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Mason City, Iowa, United States
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Sioux City, Iowa, United States
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Waterloo, Iowa, United States
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Hays, Kansas, United States
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Hutchinson, Kansas, United States
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Kansas City, Kansas, United States
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Lawrence, Kansas, United States
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Lenexa, Kansas, United States
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Topeka, Kansas, United States
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Witchita, Kansas, United States
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Ashland, Kentucky, United States
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Danville, Kentucky, United States
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Hazard, Kentucky, United States
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Lexington, Kentucky, United States
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Louisville, Kentucky, United States
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Paducah, Kentucky, United States
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Pikeville, Kentucky, United States
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Trenton, Kentucky, United States
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Baton Rouge, Louisiana, United States
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Debque, Louisiana, United States
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Lafayette, Louisiana, United States
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Lake Charles, Louisiana, United States
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Metairie, Louisiana, United States
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New Orleans, Louisiana, United States
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Shreveport, Louisiana, United States
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Slidell, Louisiana, United States
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Thiodaux, Louisiana, United States
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Bangor, Maine, United States
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Scarborough, Maine, United States
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Waterville, Maine, United States
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York Village, Maine, United States
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Baltimore, Maryland, United States
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Bethesda, Maryland, United States
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Cumberland, Maryland, United States
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Olney, Maryland, United States
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Rockville, Maryland, United States
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Towson, Maryland, United States
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Waldorf, Maryland, United States
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Beverly, Massachusetts, United States
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Boston, Massachusetts, United States
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Brockton, Massachusetts, United States
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Burlington, Massachusetts, United States
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Chicopee, Massachusetts, United States
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Lowell, Massachusetts, United States
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Mansfield, Massachusetts, United States
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Medford, Massachusetts, United States
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Pittsfield, Massachusetts, United States
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Quincy, Massachusetts, United States
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South Weymouth, Massachusetts, United States
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Springfield, Massachusetts, United States
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Stoneham, Massachusetts, United States
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Taunton, Massachusetts, United States
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Walpole, Massachusetts, United States
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Wareham, Massachusetts, United States
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Wellesley, Massachusetts, United States
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Woburn, Massachusetts, United States
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Worchester, Massachusetts, United States
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Battle Kreek, Michigan, United States
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Bay City, Michigan, United States
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Detroit, Michigan, United States
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Flint, Michigan, United States
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Free Soil, Michigan, United States
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Golfport, Michigan, United States
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Grand Rapids, Michigan, United States
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Grosse Point Woods, Michigan, United States
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Iron Mountain, Michigan, United States
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Jackson, Michigan, United States
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Kalamazoo, Michigan, United States
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Lansing, Michigan, United States
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Lapeer, Michigan, United States
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Marquette, Michigan, United States
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Midland, Michigan, United States
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Mount Clemens, Michigan, United States
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Muskegon, Michigan, United States
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Petoskey, Michigan, United States
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Poplar Buff, Michigan, United States
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Port Huron, Michigan, United States
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Roseville, Michigan, United States
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Royal Oak, Michigan, United States
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Saint Joseph, Michigan, United States
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Southfield, Michigan, United States
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Traverse City, Michigan, United States
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Ypsilanti, Michigan, United States
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Alexandria, Minnesota, United States
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Bemidji, Minnesota, United States
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Brainerd, Minnesota, United States
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Duluth, Minnesota, United States
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Maplewood, Minnesota, United States
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Minneapolis, Minnesota, United States
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Roseville, Minnesota, United States
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Saint Cloud, Minnesota, United States
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Saint Louis Park, Minnesota, United States
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Hattiesburg, Mississippi, United States
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Jackson, Mississippi, United States
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Pascagoula, Mississippi, United States
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Tupelo, Mississippi, United States
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Branson, Missouri, United States
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Chesterfield, Missouri, United States
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Columbia, Missouri, United States
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Creve Coeus, Missouri, United States
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Joplin, Missouri, United States
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Kansas City, Missouri, United States
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Poplar Bluff, Missouri, United States
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Saint Charles, Missouri, United States
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Springfield, Missouri, United States
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St Louis, Missouri, United States
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Billings, Montana, United States
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Great Falls, Montana, United States
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Helena, Montana, United States
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Grand Island, Nebraska, United States
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Lincoln, Nebraska, United States
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Omaha, Nebraska, United States
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Las Vegas, Nevada, United States
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Reno, Nevada, United States
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Hooksett, New Hampshire, United States
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Lebanon, New Hampshire, United States
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Nashua, New Hampshire, United States
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Belleville, New Jersey, United States
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Denville, New Jersey, United States
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Elizabeth, New Jersey, United States
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Englewood, New Jersey, United States
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Flemington, New Jersey, United States
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Galloway, New Jersey, United States
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Hackensack, New Jersey, United States
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Little Silver, New Jersey, United States
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Livingston, New Jersey, United States
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Long Branch, New Jersey, United States
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Mahwah, New Jersey, United States
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Manasquan, New Jersey, United States
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Montclair, New Jersey, United States
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Morristown, New Jersey, United States
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Mount Holly, New Jersey, United States
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New Brunswick, New Jersey, United States
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Newark, New Jersey, United States
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Old Bridge, New Jersey, United States
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Paramus, New Jersey, United States
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Phillipsburg, New Jersey, United States
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Plainfield, New Jersey, United States
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Pompton Plains, New Jersey, United States
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Princeton, New Jersey, United States
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Red Bank, New Jersey, United States
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Somerset, New Jersey, United States
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Summit, New Jersey, United States
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Teaneck, New Jersey, United States
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Union, New Jersey, United States
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Voorhees Township, New Jersey, United States
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Westwood, New Jersey, United States
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Albuquerque, New Mexico, United States
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Farmington, New Mexico, United States
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Las Cruces, New Mexico, United States
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Roswell, New Mexico, United States
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Santa Fe, New Mexico, United States
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Albany, New York, United States
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Bay Shore, New York, United States
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Bayside, New York, United States
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Bronxville, New York, United States
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Brooklyn, New York, United States
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Buffalo, New York, United States
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Cooperstown, New York, United States
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East Setauket, New York, United States
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East Syracuse, New York, United States
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Flushing, New York, United States
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Fresh Meadows, New York, United States
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Geneseo, New York, United States
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Glen Cove, New York, United States
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Glens Falls, New York, United States
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Goshen, New York, United States
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Great Neck, New York, United States
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Harris, New York, United States
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Huntington, New York, United States
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Huntington Station, New York, United States
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Johnson City, New York, United States
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Lake Success, New York, United States
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Malone, New York, United States
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Merrick, New York, United States
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Mineola, New York, United States
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New Hyde Park, New York, United States
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New Rochelle, New York, United States
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New York, New York, United States
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Northport, New York, United States
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Nyack, New York, United States
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Pomona, New York, United States
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Port Washington, New York, United States
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Riverhead, New York, United States
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Rochester, New York, United States
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Rockville Centre, New York, United States
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Schenectady, New York, United States
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Staten Island, New York, United States
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Suffern, New York, United States
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Syosset, New York, United States
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The Bronx, New York, United States
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Utica, New York, United States
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Valhalla, New York, United States
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Valley Stream, New York, United States
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West Islip, New York, United States
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White Plains, New York, United States
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Wiliamsville, New York, United States
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Williamsville, New York, United States
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Woodbury, New York, United States
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Asheville, North Carolina, United States
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Boone, North Carolina, United States
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Burlington, North Carolina, United States
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Charlotte, North Carolina, United States
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Concord, North Carolina, United States
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Durham, North Carolina, United States
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Elizabeth, North Carolina, United States
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Fayetteville, North Carolina, United States
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Forest City, North Carolina, United States
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Goldsboro, North Carolina, United States
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Greensboro, North Carolina, United States
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Greenville, North Carolina, United States
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Hickory, North Carolina, United States
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Kinston, North Carolina, United States
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Raleigh, North Carolina, United States
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Salisbury, North Carolina, United States
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Valdese, North Carolina, United States
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Wilmington, North Carolina, United States
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Winston-Salem, North Carolina, United States
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Bismarck, North Dakota, United States
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Fargo, North Dakota, United States
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Grand Forks, North Dakota, United States
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Akron, Ohio, United States
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Barberton, Ohio, United States
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Bryan, Ohio, United States
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Canton, Ohio, United States
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Cincinnati, Ohio, United States
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Cleveland, Ohio, United States
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Columbus, Ohio, United States
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Dayton, Ohio, United States
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Fairfield, Ohio, United States
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Finley, Ohio, United States
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Independence, Ohio, United States
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Kettering, Ohio, United States
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Mansfield, Ohio, United States
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Mentor, Ohio, United States
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Middleburg Heights, Ohio, United States
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Middletown, Ohio, United States
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Sandusky, Ohio, United States
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Toledo, Ohio, United States
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Troy, Ohio, United States
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Warrensville Heights, Ohio, United States
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Wooster, Ohio, United States
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Youngstown, Ohio, United States
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Zanesville, Ohio, United States
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Enid, Oklahoma, United States
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Lawton, Oklahoma, United States
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Oklahoma City, Oklahoma, United States
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Ponca City, Oklahoma, United States
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Stillwater, Oklahoma, United States
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Tulsa, Oklahoma, United States
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Bend, Oregon, United States
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Coos Bay, Oregon, United States
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Corvallis, Oregon, United States
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Eugene, Oregon, United States
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Klamath, Oregon, United States
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Medford, Oregon, United States
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Portland, Oregon, United States
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Salem, Oregon, United States
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Tualatin, Oregon, United States
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Allentown, Pennsylvania, United States
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Bethlehem, Pennsylvania, United States
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Bryn Mawr, Pennsylvania, United States
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Butler, Pennsylvania, United States
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Cellarsville, Pennsylvania, United States
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Danville, Pennsylvania, United States
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Drexel Hill, Pennsylvania, United States
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Dunmore, Pennsylvania, United States
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East Stroudsburg, Pennsylvania, United States
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Easton, Pennsylvania, United States
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Ephrata, Pennsylvania, United States
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Erie, Pennsylvania, United States
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Franklin, Pennsylvania, United States
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Greensburg, Pennsylvania, United States
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Harrisburg, Pennsylvania, United States
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Hazleton, Pennsylvania, United States
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Kingston, Pennsylvania, United States
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Kittanning, Pennsylvania, United States
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Lancaster, Pennsylvania, United States
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Langhorne, Pennsylvania, United States
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Langhorn, Pennsylvania, United States
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Lemoyne, Pennsylvania, United States
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Philadelphia, Pennsylvania, United States
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Phoenixville, Pennsylvania, United States
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Pittsburgh, Pennsylvania, United States
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Pottstown, Pennsylvania, United States
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Pottsville, Pennsylvania, United States
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Saint Marys, Pennsylvania, United States
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Sayre, Pennsylvania, United States
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Scranton, Pennsylvania, United States
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State College, Pennsylvania, United States
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West Reading, Pennsylvania, United States
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York, Pennsylvania, United States
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Pawtucket, Rhode Island, United States
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Providence, Rhode Island, United States
Research Site
Warwick, Rhode Island, United States
Research Site
Westerly, Rhode Island, United States
Research Site
Charleston, South Carolina, United States
Research Site
Columbia, South Carolina, United States
Research Site
Florence, South Carolina, United States
Research Site
Greenville, South Carolina, United States
Research Site
Mt. Pleasant, South Carolina, United States
Research Site
Myrtle Beach, South Carolina, United States
Research Site
Spartenburg, South Carolina, United States
Research Site
Aberdeen, South Dakota, United States
Research Site
Rapid City, South Dakota, United States
Research Site
Sioux Falls, South Dakota, United States
Research Site
Chattanooga, Tennessee, United States
Research Site
Collierville, Tennessee, United States
Research Site
Jackson, Tennessee, United States
Research Site
Johnson City, Tennessee, United States
Research Site
Knoxville, Tennessee, United States
Research Site
Memphis, Tennessee, United States
Research Site
Nashville, Tennessee, United States
Research Site
Abilene, Texas, United States
Research Site
Amarillo, Texas, United States
Research Site
Arlington, Texas, United States
Research Site
Austin, Texas, United States
Research Site
Baytown, Texas, United States
Research Site
Beaumont, Texas, United States
Research Site
Bryan, Texas, United States
Research Site
Corpus Christi, Texas, United States
Research Site
Dallas, Texas, United States
Research Site
El Paso, Texas, United States
Research Site
Fort Worth, Texas, United States
Research Site
Fredricksburg, Texas, United States
Research Site
Garland, Texas, United States
Research Site
Houston, Texas, United States
Research Site
Irving, Texas, United States
Research Site
Lewisville, Texas, United States
Research Site
Lubbock, Texas, United States
Research Site
McAllen, Texas, United States
Research Site
Mesquite, Texas, United States
Research Site
Midland, Texas, United States
Research Site
New Braunfels, Texas, United States
Research Site
Paris, Texas, United States
Research Site
Pasadena, Texas, United States
Research Site
Plano, Texas, United States
Research Site
Richmond, Texas, United States
Research Site
San Antonio, Texas, United States
Research Site
San Marcos, Texas, United States
Research Site
Sherman, Texas, United States
Research Site
Temple, Texas, United States
Research Site
Tyler, Texas, United States
Research Site
Victoria, Texas, United States
Research Site
Waco, Texas, United States
Research Site
Walla Walla, Texas, United States
Research Site
Webster, Texas, United States
Research Site
Ivins, Utah, United States
Research Site
Ogden, Utah, United States
Research Site
Salt Lake City, Utah, United States
Research Site
Bennington, Vermont, United States
Research Site
Rutland, Vermont, United States
Research Site
Abington, Virginia, United States
Research Site
Charlottesville, Virginia, United States
Research Site
Chesapeake, Virginia, United States
Research Site
Danville, Virginia, United States
Research Site
Fairfax, Virginia, United States
Research Site
Fredericksburg, Virginia, United States
Research Site
Hampton, Virginia, United States
Research Site
Lynchburg, Virginia, United States
Research Site
Newport News, Virginia, United States
Research Site
Norfolk, Virginia, United States
Research Site
Portsmouth, Virginia, United States
Research Site
Richmond, Virginia, United States
Research Site
Roanoke, Virginia, United States
Research Site
Williamsburg, Virginia, United States
Research Site
Woodridge, Virginia, United States
Research Site
Auburn, Washington, United States
Research Site
Bremerton, Washington, United States
Research Site
Kennewick, Washington, United States
Research Site
Kirkland, Washington, United States
Research Site
Mount Vernon, Washington, United States
Research Site
Olympia, Washington, United States
Research Site
Renton, Washington, United States
Research Site
Seattle, Washington, United States
Research Site
Spokane, Washington, United States
Research Site
Tacoma, Washington, United States
Research Site
Vancouver, Washington, United States
Research Site
Clarksburg, West Virginia, United States
Research Site
Huntington, West Virginia, United States
Research Site
Morgantown, West Virginia, United States
Research Site
Princeton, West Virginia, United States
Research Site
Wheeling, West Virginia, United States
Research Site
Appleton, Wisconsin, United States
Research Site
Eau Claire, Wisconsin, United States
Research Site
Green Bay, Wisconsin, United States
Research Site
Janesville, Wisconsin, United States
Research Site
La Crosse, Wisconsin, United States
Research Site
Madison, Wisconsin, United States
Research Site
Manitowoc, Wisconsin, United States
Research Site
Marshfield, Wisconsin, United States
Research Site
Milwaukee, Wisconsin, United States
Research Site
Racine, Wisconsin, United States
Research Site
Rhinelander, Wisconsin, United States
Research Site
Sheboygan, Wisconsin, United States
Research Site
Waukesha, Wisconsin, United States
Research Site
Wausau, Wisconsin, United States
Research Site
Cheyenne, Wyoming, United States
Countries
Review the countries where the study has at least one active or historical site.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
1839IL/0050
Identifier Type: -
Identifier Source: org_study_id
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