Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
OBSERVATIONAL
1996-04-30
2000-12-31
Brief Summary
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This project has two objectives: A) To define the mechanism of impaired bile acid absorption in hypertriglyceridemia (specifically we will determine if the active or passive component of absorption is abnormal) and B) to determine the contribution of an alternative pathway of bile acid synthesis which begins with 27-hydroxylation of cholesterol. Because 27-hydroxylase is present in endothelial cells as well as liver, this pathway may play a role in removal of cholesterol from incipient atherosclerotic plaque.
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Detailed Description
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Conditions
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Study Design
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PROSPECTIVE
Eligibility Criteria
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Inclusion Criteria
18 Years
75 Years
ALL
Yes
Sponsors
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US Department of Veterans Affairs
FED
Principal Investigators
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Norman Javitt, M.D.
Role:
Alan Hofmann, M.D.
Role:
Loren Zech, M.D.
Role:
Locations
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VA Medical Center
Minneapolis, Minnesota, United States
Countries
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Other Identifiers
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GAST-026-95F
Identifier Type: -
Identifier Source: org_study_id
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