Lifestyle Interventions to Reduce Diabetes Risk

NCT ID: NCT00006162

Last Updated: 2010-03-02

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Study Classification: INTERVENTIONAL
• Study Start Date: 1994-10-31
• Study Completion Date: 1999-04-30

Brief Summary

Type 2 diabetes is more frequent in Japanese Americans than in Japan or the U.S. non-Hispanic white population. This appears to be due to the effects of ''westernization'' to bring out metabolic changes that lead to diabetes. This study will look at whether increased physical activity and dietary changes will reduce or prevent the metabolic changes that lead to type 2 diabetes in Japanese Americans who have impaired glucose tolerance, a condition intermediate between normal glucose tolerance and diabetes.

Conditions

Glucose Intolerance; Diabetes Mellitus, Type 2

Study Design

• Allocation Method: RANDOMIZED
• Primary Study Purpose: PREVENTION

Interventions

exercise and diet

Intervention Type: BEHAVIORAL

Eligibility Criteria

Inclusion Criteria

• Japanese American
• Confirmed impaired glucose tolerance
• Able to fill out questionnaires

Exclusion Criteria

• Significant exercise-restricting disease
• Poorly controlled hypertension
• Psychiatric disease or dementia
• Already on unusually restrictive diet
• Use of hypolipidemic drugs
• Use of tobacco
• Abnormal blood screening tests
• ECG evidence of ischemic heart disease at rest
• Abnormal maximal Bruce treadmill test

• Minimum Eligible Age: 40 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NIH

Sponsor Role: lead

Locations

University of Washington

Seattle, Washington, United States

Countries

United States

Other Identifiers

1R01DK048152

Identifier Type: NIH

Identifier Source: secondary_id

View Link

fujimotow (completed)

Identifier Type: -

Identifier Source: org_study_id